en Nephrology Nephrology Original Article Original Article <span style="font-size:14px;"><span style="font-family:Times New Roman;"><span style="line-height:14pt"><b><i><span style="color:blue">Background</span></i></b><i><span style="color:blue">:</span></i> Sleep disorders frequently affect end-stage renal disease patients on dialysis. However, the relationship between sleep quality and residual kidney function is still unclear. Therefore, this study aimed to investigate this relationship.</span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Methods:</span></i></b> In this analytical cross-sectional study, 225 patients who were referred to dialysis centers were studied, and based on renal function, they were classified into two groups with and without residual kidney function. The study employed the Pittsburgh Sleep Quality Index questionnaire to evaluate sleep quality. Multiple linear regression was utilized to determine the factors affecting sleep quality with a significance level consideration at p<0.05.</span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Results:</span></i></b> The mean age of patients was 58.23 &plusmn; 13.50 years. 58.7% of patients were males. The problem of serious and very serious sleep in the Sleep latency and sleep duration has been more than other components. 72% of hemodialysis patients had poor sleep quality. In the multiple linear regression model, age (&beta; = 0.442, 95% CI: 0.096, 0.788), sex (&beta; = -0.847, 95% CI: -1.641, -0.054), Body mass index (&beta; = 0.153, 95% CI: 0.058, 0.249) and dialysis duration (&beta; = 0.097, 95% CI: 0.002, 0.192) were independently and significantly associated with sleep quality score. However, there was no statistically significant relationship between sleep quality and residual kidney function. </span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Conclusion</span></i></b><i><span style="color:blue">:</span></i> In conclusion, poor sleep quality is very common in patients undergoing hemodialysis. Therefore, sleep disorders in hemodialysis patients should be considered as one of the most challenging problems by healthcare providers, and early diagnosis and intervention are essential to improve sleep quality. </span></span></span><br> &nbsp; Hemodialysis, Residual kidney function, Pittsburgh sleep quality index, Sleep disorders 682 689 http://caspjim.com/browse.php?a_code=A-10-3098-1&slc_lang=en&sid=1 Elham Ramezanzade rz.elham58@gmail.com 100319475328460050055 100319475328460050055 No Razi Clinical Research Development Center, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran Masoud Khosravi drmasoud91@yahoo.com 100319475328460050056 100319475328460050056 No Urology Research Center, Razi Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran Alireza Jafarinezhad dr.a.jafarinezhad@gums.ac.ir 100319475328460050057 100319475328460050057 No Razi Clinical Research Development Center, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran Sepideh Sadeghi Dehbane sepide.sd.d@gmail.com 100319475328460050058 0009-0002-9706-0757 No Razi Clinical Research Development Center, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran Mirsaeed Attarchi msattarchi@yahoo.com 100319475328460050059 100319475328460050059 Yes Department of Forensic Medicine, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran