Caspian Journal of Internal Medicine

en Does vitamin D status correlate with clinical and biochemical features of polycystic ovary syndrome in high school girls? Internal Internal Original Article Original Article Abstract  Background: Prevalence of polycystic ovary syndrome (PCOs) is increasing particularly among the female adolescents and young women. It has been hypothesized that disturbance in calcium and vitamin-D metabolism may affect the symptoms of this syndrome. This study was designed to investigate the relationship between vitamin-D and calcium with metabolic parameters and other characteristics of the PCOs. Methods: The study included 192 Iranian girls (16-20 years old), of whom 104 had PCOs and 88 were non-PCOs controls. Serum 25(OH) D and calcium level was measured. Anthropometric components, endocrine, metabolic components and insulin resistance were determined in PCOs subjects.  Results: Mean 25 (OH) D was significantly lower in cases (9.7±4.8) than controls (12.3±11.9) but calcium level did not differ between the two groups (9.3±0.3 vs 9.4±0.4). No significant correlations were found between 25(OH) D levels and lipid profile, FBS, fasting insulin endocrine parameters such as testosterone, free testosterone, FSH, LH, and prolactin.  Conclusion: Although hypovitamionos D was common is PCOs but did not correlate with clinical features or complications of obesity and insulin resistance PCO like severity of syndrome between vitamin-D deficiency and its severity with some features and complications of PCOs including obesity, insulin resistance.   Keywords: Polycystic ovary syndrome, Vitamin-D, Calcium, Younger girls. 202 208 http://caspjim.com/browse.php?a_code=A-10-62-198&slc_lang=en&sid=1 Reza Ghadimi 100319475328460034249 100319475328460034249 No Sedighe Esmaeilzadeh sesmael@yahoo.com 100319475328460034250 100319475328460034250 Yes Marmar Firoozpour 100319475328460034251 100319475328460034251 No Asal Ahmadi 100319475328460034252 100319475328460034252 No