en Internal Internal Original Article Original Article <font face="Times New Roman" size="3"> </font><p style="margin: 0cm 0cm 0pt 176.05pt"><b><i><span style="color: blue"><font face="Times New Roman" size="3">Abstract</font></span></i></b></p><font face="Times New Roman" size="3"> </font><p style="margin: 0cm 0cm 0pt 161.6pt text-indent: 0cm"><font face="Times New Roman"><b><i><span style="color: blue font-size: 10pt">Background: </span></i></b><span style="font-size: 10pt">Erectile dysfunction (ED) is common in cardiovascular disease (CVD) and indicates a complication of coronary artery bypass graft surgery (CABG). This study was designed to evaluate the status of erectile dysfunction in patients with CAD before and after CABG surgery.</span></font></p><font face="Times New Roman" size="3"> </font><p style="margin: 0cm 0cm 0pt 161.6pt text-indent: 0cm"><font face="Times New Roman"><b><i><span style="color: blue font-size: 10pt">Methods:</span></i></b><span style="font-size: 10pt"> We designed a prospective cohort study on male patients candidates for elective on-pump CABG between June 2006 to October 2012 in 3 hospitals in Sari, Iran (Fatemeh Zahra, Shafa and Nime-Shaban Hospitals). Patient’s primary data were collected based on the International Index of Erectile Function questionnaire (IIEF-5) at baseline 6 months after surgery. The severity of dysfunction was categorized as, normal, mild to moderate and moderate to severe based on IIEF score.</span></font></p><font face="Times New Roman" size="3"> </font><p style="margin: 0cm 0cm 0pt 161.6pt text-indent: 0cm"><font face="Times New Roman"><b><i><span style="color: blue font-size: 10pt">Results:</span></i></b><span style="font-size: 10pt"> Four hundred twenty-six male patients with mean age of 58.69±12.49 years participated in this study. 166 patients had DM (38.96%) 230 patients had hypertension (54%). 307 patients had three-vessel impairment (72.07%) and 119 patients with one or two vessel impairment (27.93%). The </span><span style="font-size: 10pt mso-fareast-font-family: Arial">15.02%, 18.07%, 23%, 31.92% and 11.97%, at baseline changed to 16.90%, 19.95%, 23.71%, 32.22% and 8.21%, at endpoint (P=0.01). Also, the mean</span><span style="font-size: 10pt">±</span><span style="font-size: 10pt mso-fareast-font-family: Arial">SD of IIEF-5 score before and after surgery was 13.95</span><span style="font-size: 10pt">±5.44</span><span style="font-size: 10pt mso-fareast-font-family: Arial"> and </span><span style="font-size: 10pt">14.20±5.69, respectively (P=0.001). </span></font></p><font face="Times New Roman" size="3"> </font><p style="margin: 0cm 0cm 0pt 161.6pt text-indent: 0cm"><font face="Times New Roman"><b><i><span style="color: blue font-size: 10pt">Conclusion: </span></i></b><span style="font-size: 10pt"><span style="mso-spacerun: yes"> </span>The result of our study shows that on-pump CABG surgery has a positive effect on the improvement of erectile dysfunction 6 months after surgery.</span></font></p><font size="3"> </font> Keywords: Erectile dysfunction, Coronary artery bypass graft surgery, IIEF-5. 209 212 http://caspjim.com/browse.php?a_code=A-10-62-199&slc_lang=en&sid=1 Shervin Ziabakhsh Tabary 10031947532846002443 10031947532846002443 No Farzad Mokhtari-Esbuie 10031947532846002444 10031947532846002444 No Mehran Fazli shervin.zia@gmail.com 10031947532846002445 10031947532846002445 Yes