en Cardiology Cardiology Original Article Original Article <span style="font-size:14px;"><span style="font-family:Times New Roman;"><span style="line-height:14pt"><b><i><span style="color:blue">Background</span></i></b><i><span style="color:blue">:</span></i> Coronary heart disease (CHD) is an underlying cardiac condition contributing to increased COVID-19 mortality and morbidity which can be assessed by several diagnosis methods including coronary artery calcification (CAC). The goal of this study was to find out if there were potential links between CAC, clinical findings, severity of COVID-19, and in-hospital outcomes. </span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Methods:</span></i></b> This retrospective study evaluated 551 suspected patients admitted to teaching hospitals of the Babol University of Medical Sciences, Babol, Iran, from March to October 2021. Data included previous diseases, comorbidities, clinical examinations, routine laboratory tests, demographic characteristics, duration of hospitalization, and number of days under ventilation were recorded in a checklist.</span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Results:</span></i></b> Findings of current study provide evidence of a significant relationship between coronary artery calcification (CAC) and in-hospital mortality. Additionally, we observed significant correlations between CAC and several clinical parameters including age, duration of hospitalization, pulse rate, maximum blood pressure, erythrocyte sedimentation rate (ESR), blood urea nitrogen (BUN), neutrophil count, white blood cell (WBC) count, and oxygen saturation. However, we did not observe a significant association between CAC and the severity index of COVID-19. In addition, logistic regression tests did not find a significant value of CAC to predict in-hospital mortality.</span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Conclusion: </span></i></b><span style="color:black">Our findings showed a significant relationship between CAC and in-hospital mortality.</span><span style="font-size:10.0pt"></span></span></span></span><br> &nbsp; Coronary heart disease, COVID-19, Hospitalization, Morbidity, Mortality, Coronary artery calcification 466 471 http://caspjim.com/browse.php?a_code=A-10-2169-3&slc_lang=en&sid=1 Saeed Abrotan abrotan@yahoo.com 100319475328460048989 100319475328460048989 No Department of Cardiology, School of Medicine, Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran Farzad Jalali sfjalali42@yahoo.com 100319475328460048990 100319475328460048990 Yes Department of Cardiology, School of Medicine, Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran Mohammad Taghi Hedayati Goudarzi drmohammadhedayati@yahoo.com 100319475328460048991 100319475328460048991 No Department of Cardiology, School of Medicine, Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran Iraj Jafaripour iraj595@yahoo.com 100319475328460048992 100319475328460048992 No Department of Cardiology, School of Medicine, Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran Mehrdad saravi mehrdadsaravi@gmail.com 100319475328460048993 100319475328460048993 No Department of Cardiology, School of Medicine, Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran Naghmeh Ziaie amiri ziaiexn@yahoo.com 100319475328460048994 100319475328460048994 No Department of Cardiology, School of Medicine, Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran Roghayeh Pourkia Dr.pourkia@yahoo.com 100319475328460048995 100319475328460048995 No Department of Cardiology, School of Medicine, Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran Kamyar Amin persicacamyar@yahoo.com 100319475328460048996 100319475328460048996 No Department of Cardiology, School of Medicine, Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran Ali Bijani alibijani@yahoo.com 100319475328460048997 100319475328460048997 No Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Masoumeh Bayani m_baiany@yahoo.com 100319475328460048998 100319475328460048998 No Infectious Diseases and Tropical Medicine Research Center, Health Research Institute, Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran Soraya Khafri khafri@yahoo.com 100319475328460048999 100319475328460048999 No Infertility and Reproductive Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Milad Bakhshi 100319475328460049000 100319475328460049000 No Student Research Committee, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran Saeed kargar-soleimanabad saeed1376.mu@gmail.com 100319475328460049001 100319475328460049001 No Student Research Committee, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran Erfan Ghadirzadeh er.ghadirzadeh@gmail.com 100319475328460049002 100319475328460049002 No Student Research Committee, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran