en Internal Internal Original Article Original Article <p style="margin-top: 0cm; margin-right: 0cm; margin-bottom: 0pt;"><span style="color:#0000FF;"><b style="font-family: &quot;Times New Roman&quot;;"><i>Background: </i></b></span><span style="font-family: &quot;Times New Roman&quot;; font-size: 10pt;">Interleukin-6 (IL-6) has a major role in hematopoiesis, immune and acute phase response and its serum level seems to be associated with the mode of delivery. The purpose of this study was to compare the level of IL-6 in mothers who delivered via cesarean section and vaginally</span><span style="font-family: &quot;Times New Roman&quot;;">.</span></p> <span style="color:#0000FF;"><b style="font-family: &quot;Times New Roman&quot;;"><i>Methods:</i></b></span><span style="font-family: &quot;Times New Roman&quot;; font-size: 10pt;"> This cross-sectional study was done on 40 mothers with vaginal delivery and 40 mothers with elective cesarean delivery<b>&nbsp;</b>in 2012 in Ayatollah Rouhani Teaching Hospital in Babol, northern Iran. Five ml blood samples were taken from each mother. Blood samples were examined by<span dir="rtl"><font size="2">&nbsp;</font></span>enzyme-immune assay for the determination of IL-6 in both mothers and neonates. Other information, such as the mother&#39;s age, newborn sex, gravity, parity, the number of live births of each mother, and the status of infants in terms of being term or pre-term, was recorded.</span><br> <span style="font-family: &quot;Times New Roman&quot;; color: rgb(0, 0, 255);"><b><i>Results:</i></b></span><span style="font-family: &quot;Times New Roman&quot;; font-size: 10pt;"> The mean age of cesarean section and vaginal delivery patients was (29&plusmn;5.01) yrs and (27.3&plusmn; 4.93) yrs. The maternal IL-6 concentration in vaginal birth (170.13 &plusmn;15.9) was significantly (p<0.05</span><font style="font-family: &quot;Times New Roman&quot;;"><span dir="rtl" lang="AR-SA">(</span></font><span style="font-family: &quot;Times New Roman&quot;;">higher</span><span style="font-family: &quot;Times New Roman&quot;; font-size: 10pt;"> than cesarean section (33&plusmn;29.94).</span><br> <span style="font-family: &quot;Times New Roman&quot;; color: rgb(0, 0, 255);"><b><i>Conclusion: </i></b></span><span style="font-family: &quot;Times New Roman&quot;; font-size: 10pt;">The result shows that serum IL-6 levels in patients with vaginal delivery was higher than those with elective cesarean section delivery. So, vaginal delivery is preferred for all patients except those in whom vaginal delivery is contraindicated.</span><br> <font face="Times New Roman" size="3">&nbsp;</font> <p style="margin: 0cm 0cm 0pt 161.6pt text-indent: 0cm"><font face="Times New Roman"><span style="font-size: 10pt mso-bidi-language: FA"></span></font></p> <font face="Times New Roman" size="3">&nbsp;</font> Keywords: Vaginal delivery, elective cesarean section, interleukin-6 223 226 http://caspjim.com/browse.php?a_code=A-10-62-202&slc_lang=en&sid=1 Mohsen Haghshenas Mojaveri matia.mojaveri@yahoo.com 100319475328460015380 100319475328460015380 Yes Non-Communicable Pediatric Diseases Research Center, Babol University of Medical Sciences, Babol, Iran Iraj Mohammadzadeh 100319475328460015381 100319475328460015381 No Zinat Al-Sadat Bouzari 100319475328460015382 100319475328460015382 No Zahra Akbarian Rad 100319475328460015383 100319475328460015383 No Ghamar Haddad 100319475328460015384 100319475328460015384 No Reza Alizadeh-Navaei 100319475328460015385 100319475328460015385 No