en Internal Internal case report case report <p><font face="Times New Roman" size="3"> </font><b><i><span style="color: blue"><font face="Times New Roman" size="3">Abstract</font></span></i></b><font face="Times New Roman" size="3"> </font></p><p><font face="Times New Roman" size="3"> </font><font face="Times New Roman"><b><i><span style="color: blue font-size: 10pt">Background: </span></i></b><span style="color: black font-size: 10pt">HELLP syndrome is an important complications in pregnancy which increases maternal and fetal mortality. This disease usually remits with supportive treatment which includes prescription of corticosteroid, magnesium sulfate, stabilization of mother and pregnancy termination. Plasmapheresis is a treatment of choice which improves clinical outcomes in complicated cases. </span></font></p><p><font face="Times New Roman"><span style="color: black font-size: 10pt"></span></font><font face="Times New Roman"><b><i><span style="color: blue font-size: 10pt">Case presentation:</span></i></b><span style="color: black font-size: 10pt"> A 22-year-old woman with coagulopathy and respiratory distress and 33-year-old woman with a history of cerebellar medulloblastoma at 32-weeks’ gestation developed thrombocytopenia due to HELLP syndrome were treated with plasmapheresis were described.</span></font></p><font face="Times New Roman" size="3"> </font><b><i><span style="color: blue font-family: "Times New Roman",serif font-size: 10pt mso-bidi-language: AR-SA mso-fareast-font-family: "Times New Roman" mso-ansi-language: EN-US mso-fareast-language: EN-US">Conclusion: </span></i></b><span style="color: black font-family: "Times New Roman",serif font-size: 10pt mso-bidi-language: AR-SA mso-fareast-font-family: "Times New Roman" mso-ansi-language: EN-US mso-fareast-language: EN-US">Plasmapheresis can significantly improve the outcome of patients with HELLP syndrome who are unresponsive to conservative therapy</span> HELLP syndrome, Plasmapheresis, Thrombocytopenia 243 247 http://caspjim.com/browse.php?a_code=A-10-62-205&slc_lang=en&sid=1 Jamshid Vafaeimanesh 10031947532846002482 10031947532846002482 No Azam Nazari 10031947532846002483 10031947532846002483 No Fatemeh Hosseinzadeh Fatima.hzade@gmail.com 10031947532846002484 10031947532846002484 Yes