en Oncology Oncology Original Article Original Article <p><span style="font-size:14px"><span style="font-family:Times New Roman"><strong><em><span style="color:blue">Background</span></em></strong><em><span style="color:blue">:</span></em> The cost of anticancer drugs and their wastage has become a major concern for patients and health policy makers in developing countries. To date, no figures have been reported on the rate of loss of anticancer drugs in Iran. Therefore, we aimed to conduct a real-world analysis on the anticancer drug wastage in a public hospital.<br> <strong><em><span style="color:blue">Methods:</span></em></strong> During a 3-month time span, we observationally collected drug information of all patients admitted for receiving anticancer drugs in the inpatient or outpatient unit of chemotherapy center by two oncology nurses. The amount of drug wastage and its financial cost were calculated based on the price approved by the Food and Drug Administration (FDA) of Islamic Republic of Iran (IRI) during the survey period.<br> <strong><em><span style="color:blue">Results:</span></em></strong> A total of<strong> </strong>626 patients were admitted for receiving twenty-four injectable anticancer drugs in 2023 infusions. The percentage of total drug wastage was 9.31% (95% CI, 5.90 &ndash;12.71%)<span dir="RTL" lang="AR-SA">.</span> Overall, these results indicated that the cost of drug wastage in this 3-month period was roughly 31,473 US dollars (USD) and estimated annual cost of wastage was nearly 125,894 USD (5,287,553,080 Iranian Rial).<br> <strong><em><span style="color:blue">Conclusion</span></em></strong><em><span style="color:blue">:</span></em> This is the first report of investigating anticancer drug wastage in Iran. According to this real-world survey, it was shown that the amount of drug wastage in this center is substantial and imposes a heavy financial burden on patients and the health system that need to be taken into account by policy makers.</span></span><br> &nbsp;</p> Cancer, leftover drug, economic health, economic burden 314 319 http://caspjim.com/browse.php?a_code=A-10-3206-2&slc_lang=en&sid=1 Yahya Baharvand Iran Nia y.b.i31333@gmail.com 100319475328460052268 100319475328460052268 No Department of Internal Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran Zahra Nourolahi zakieh.n82@gmail.com 100319475328460052269 100319475328460052269 No Department of Internal Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran Fatemeh Goudarzi fatemehgoudarzi871@gmail.com 100319475328460052270 100319475328460052270 No School of Nursing and Midwifery, Lorestan University of Medical Sciences, Khorramabad, Iran Roya Fouladi foladifoladi22@gmail.com 100319475328460052271 100319475328460052271 No School of Nursing and Midwifery, Lorestan University of Medical Sciences, Khorramabad, Iran Shahram Ahmadi Somaghian shahrama20@gmail.com 100319475328460052272 100319475328460052272 Yes Razi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran Rasool Mohammadi rasool.mehr2002@gmail.com 100319475328460052273 100319475328460052273 No Nutritional Health Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran