en Cardiology Cardiology Original Article Original Article <span style="font-size:14px;"><span style="font-family:Times New Roman;"><span style="line-height:14pt"><b><i><span style="color:blue">Background</span></i></b><i><span style="color:blue">:</span></i> <span lang="EN-IN">To study the association of plasma fibrinogen & total cholesterol levels, incidences, prevalence, and gender wise distribution in different etiologies of stroke.</span></span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Methods:</span></i></b> <span lang="EN-IN">Fibrinogen & total cholesterol levels, prevalence, incidences, comorbidities, and different etiologies were assessed along with routine investigations and radiology inputs as per investigator&rsquo;s discretion. </span>The overall median values were represented in graphically format in MS-Excel. <span lang="EN-IN" style="font-size:10.0pt"></span></span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Results:</span></i></b> 292 Males: 218 females. Age 30 to 80 years. Among, 25.1% diabetic, 38.9 % hypertension (HTN) and 31% diabetes + HTN. 5 % diabetes + HTN + dyslipidemia and other comorbidities. Overall, 73% had ischemic stroke (IS) & 27 % have hemorrhagic stroke (HS). Hemiparesis in 76.5 %. Mean Fibrinogen elevated in 81% and range was 934&plusmn;20 mg/dL. Total cholesterol level increased in 73.2% & range was 365&plusmn;10 mg/dL. The HS patients were experienced headache 77 (19.60%) and vomiting 34 (24.6%) than IS patients. As per radiological finding, the territory of Middle Cerebral Artery was the ordinary location of arterial territory infarctions in the IS form that was present in 213 (57.2%) subjects following that in the anterior side of cerebral artery in 89 (23.92%) and posterior cerebral artery was 44 (11.82%). Arterial flutter found in 56 (10.9%), Structural heart disease present in 30 (5.88%), family history of stroke in 28 (5.49%). </span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Conclusion</span></i></b><i><span style="color:blue">:</span></i> <span lang="EN-IN">Elevated fibrinogen & total cholesterol levels are independent significant primary biomarkers elevated with incidences of CV stroke. Stroke was higher in ischemic stroke group. </span></span></span></span><br> &nbsp; Independently, Prevalence, Incidences, Comorbid and Stroke 525 535 http://caspjim.com/browse.php?a_code=A-10-3224-1&slc_lang=en&sid=1 Komal Rana dr.komalrana1990@gmail.com 100319475328460053349 0009-0004-3874-1805 No Department of Medicine, Parul Sevashram Hospital (PSH), Parul Institute of Medical Sciences and Research (PIMSR), Parul University, Vadodara, Gujarat, India Tarun Kumar Chavda chavdatarun2@gmail.com 100319475328460053350 0009-0001-6042-1435 No Department of Medicine, Kiran Medical College & Science, Vadod. Surat, Gujarat, India Sonal Chavda sonalchavda911@gmail.com 100319475328460053351 0009-0000-8389-3543 No Department of Medicine, Kiran Medical College & Science, Vadod. Surat, Gujarat, India Chetan Sonkar chetansonkar111@gmail.com 100319475328460053352 100319475328460053352 Yes Department of Medicine, Parul Sevashram Hospital (PSH), Parul Institute of Medical Sciences and Research (PIMSR), Parul University, Vadodara, Gujarat, India Krishna Soni krishnasoni0908@gmail.com 100319475328460053353 0009-0005-4485-6198 No Department of Medicine, Parul Sevashram Hospital (PSH), Parul Institute of Medical Sciences and Research (PIMSR), Parul University, Vadodara, Gujarat, India Krina Patel krinu111@gmail.com 100319475328460053354 0009-0008-6497-8610 No Department of Medicine, Parul Sevashram Hospital (PSH), Parul Institute of Medical Sciences and Research (PIMSR), Parul University, Vadodara, Gujarat, India Nancy Vaja nancyvaja333@gmail.com 100319475328460053355 0009-0007-2684-2029 No Department of Medicine, Parul Sevashram Hospital (PSH), Parul Institute of Medical Sciences and Research (PIMSR), Parul University, Vadodara, Gujarat, India Sanjay Vahora vahorasanya@gmail.com 100319475328460053356 0009-0005-0462-2805 No Department of Medicine, Parul Sevashram Hospital (PSH), Parul Institute of Medical Sciences and Research (PIMSR), Parul University, Vadodara, Gujarat, India Amal Kumar Bhattacharya amal_akb@rediffmail.com 100319475328460053357 0009-0006-4719-7367 No Department of Medicine, Parul Sevashram Hospital (PSH), Parul Institute of Medical Sciences and Research (PIMSR), Parul University, Vadodara, Gujarat, India