en Nephrology Nephrology Original Article Original Article <span style="font-size:14px;"><span style="font-family:Times New Roman;"><span style="line-height:14pt"><b><i><span style="color:blue">Background</span></i></b><i><span style="color:blue">:</span></i> Opportunistic infection after transplantation is a serious problem, with <i>Toxoplasma Gondii (T.gondii)</i> and cytomegalovirus being the most concerning infections. The objective of this research was to examine the seroepidemiology of the <i>T. gondii</i> virus among kidney transplant recipients at Sina Hospital in Tehran from 2017 to 2021.</span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Methods:</span></i></b> A total of 342 kidney transplant patients participated in this cross-sectional study using the census method after obtaining consent. Data were collected by reviewing medical records and the transplant database, including demographic characteristics and infectious tests related to kidney transplantation. The collected information was entered into SPSS18 software.</span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Results:</span></i></b> The age of the subjects ranged from 10 to 73 years, with 125 patients having kidney failure due to ERDS. The rate of exposure to T. gondii in kidney transplant patients was 54.2%. 125 patients experiencing kidney failure due to ERDS. In kidney transplant patients, the exposure rate to <i>T. gondii</i> was 54.2%. There is a positive correlation between <i>TOX IgG</i> and age (r= 0.12, P = 0.02). There is a positive correlation between <i>CMV IgG</i> and the time elapsed since kidney transplantation (r = 0.11, P = 0.03) and <i>TOX IgG</i> (r = 0.13, p < 0.01). Gender was found not to predict <i>EBV.IgG </i>(&beta;&thinsp;=&thinsp;0.787, p&thinsp;<&thinsp;0.21<i>), CMV.IgG </i>(&beta;&thinsp;=&thinsp;4.752, p&thinsp;<&thinsp;0.071),<i> TOX.IgG </i>(&beta;&thinsp;=&thinsp;1.154, p&thinsp;<&thinsp;0.256) based on regression tests.</span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Conclusion</span></i></b><i><span style="color:blue">:</span></i> Physicians should be aware of preventive measures and should consider early diagnosis in cases of compatible symptoms. Screening for anti-Toxoplasma IgM antibodies in potential donors is recommended.<span style="font-size:10.0pt"></span></span></span></span><br> &nbsp; Seroepidemiology, kidney transplant, EBV, IgG, CMV.IgG, TOX.IgG 507 512 http://caspjim.com/browse.php?a_code=A-10-2354-2&slc_lang=en&sid=1 Marzieh Latifi marziye_latifi@yahoo.com 100319475328460053335 100319475328460053335 No Department of Public Health, School of Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Iran Habib Rahban Habibrahban.md@gmail.com 100319475328460053336 100319475328460053336 No Creighton University School of Medicine, St. Joseph Hospital and Medical Center, Department of Cardiovascular Disease, Phoenix, Arizona Elahe Pourhosein elahepoorhosein1990@gmail.com 100319475328460053337 100319475328460053337 No Organ Procurement Unit, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran Tannaz Hajialireza Tehrani tannaz.tehrani19@gmail.com 100319475328460053338 0009-0002-2050-1075 No Sina Organ Procurement Unit, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran. Parisa Mahjoobi pppmahjobi@yahoo.com 100319475328460053339 100319475328460053339 No Department of medical parasitology and mycology, school of medicine, alborz university of medical sciences, Alborz, Iran. Sanaz Dehghani Sanaz_Dehghani2002@yahoo.com 100319475328460053340 100319475328460053340 Yes Organ Procurement Unit, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran