en Cardiology Cardiology Original Article Original Article <span style="font-size:14px;"><span style="font-family:Times New Roman;"><span style="line-height:14pt"><b><i><span style="color:blue">Background</span></i></b><i><span style="color:blue">:</span></i> Cardiovascular diseases (CVDs) are a significant cause of morbidity and mortality worldwide, particularly among the Iranian population. Assessing left ventricular (LV) dimensions and interventricular septum (IVS) thickness is crucial in diagnosing and managing various cardiac conditions. This study aimed to compare LV dimensions and IVS thickness using electrocardiogram (ECG) gated computed tomography angiography (CTA) and echocardiography.</span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Methods:</span></i></b> A cross-sectional study was conducted on 160 Iranian individuals without known CVD from March to September 2023 in Hospital, Tabriz, Iran. Participants underwent both ECG-gated CTA and echocardiography for assessment of LV dimensions and IVS thickness. Measurements were performed by experienced radiologists and cardiologists, respectively. Echocardiography and CTA were analyzed for their correlation using Pearson&#39;s correlation coefficient. Statistical analysis was conducted using SPSS V25 software.<b> </b></span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Results:</span></i></b> The study revealed a significant correlation between various LV dimensions and wall thickness measurements obtained from echocardiography and CTA (p<0.000). Strong and significant correlations were found in measurements taken from different views and regions of the heart, including the parasternal long-axis (PLAX) view, Mid and Base views, and the anteroseptal and inferoseptal regions (p<0.000). Echocardiography measurements also showed significant correlations, with varying strengths.</span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Conclusion</span></i></b><i><span style="color:blue">:</span></i> The comparative analysis of LV dimensions and IVS thickness using ECG-gated CTA and echocardiography demonstrated significant correlations, suggesting the potential clinical utility of both imaging techniques in diagnosing and managing CVD in the Iranian population. The 4-chamber and PSAX methods can be used interchangeably to measure interventricular septum thickness. Further research is required to validate and expand upon these results.</span></span></span><br> &nbsp; Heart Ventricles, Ventricular Septum, Computed Tomography Angiography, Echocardiography, Electrocardiographyyosefzadeh 692 699 http://caspjim.com/browse.php?a_code=A-10-2529-12&slc_lang=en&sid=1 Naser Khezerlouy-Aghdam nkhezerlou90@gmail.com 100319475328460054614 100319475328460054614 No Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran Shahla Meshgi skyshahla13@yahoo.com 100319475328460054615 100319475328460054615 No Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran Zahra Hosnavi drhosnavi.cardio@gmail.com 100319475328460054616 0009-0005-6275-825X No Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran Haleh Bodagh haleh.bodagh@gmail.com 100319475328460054617 100319475328460054617 No Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran Mohammadreza Motazedian Mohammadreza.motazedian@gmail.com 100319475328460054618 100319475328460054618 No Fassa University of Medical Sciences, Fassa, Iran Razieh Parizad r_pariad2003@yahoo.com 100319475328460054619 100319475328460054619 No Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran Asma Yosefzadeh Yousefzadehasma@yahoo.com 100319475328460054620 0009-0001-3713-0306 Yes Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran