en Cardiology Cardiology Original Article Original Article <span style="font-size:14px;"><span style="font-family:Times New Roman;"><span style="line-height:14pt"><b><i><span style="color:blue">Background</span></i></b><i><span style="color:blue">:</span></i> Analyzing the clinical efficacy and mechanism of action of cardiac rehabilitation after revascularization for coronary multibranch lesions.</span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Methods:</span></i></b> 150 patients with multiple coronary artery lesions were selected for the study from July 2022 to March 2023, and were randomly divided into observation group (75 cases, complete revascularization + cardiac rehabilitation intervention) and control group (75 cases, complete revascularization). The level of patients&#39; 6 min walking experiment, quality of life, cardiac function indexes, and laboratory indexes were analyzed.</span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Results:</span></i></b> The level of 6-min walking test was significantly higher in the observation group than in the control group (p<0.05); the quality of life of patients in the observation group was significantly higher than that of the control group (p<0.05); the levels of left ventricular end-systolic internal diameter (LVESD), left ventricular end-diastolic internal diameter (LVEDD), left ventricular pressure (LVP), and interventricular septal thickness (LVS) in patients in the observation group were significantly lower than that of the control group; and the level of LV ejection&nbsp; fraction (LVEFA) levels were significantly higher than those of the control group (P=0.00); serum homocysteine (Hcy) and blood uric acid (SUA) levels of patients in the observation group were significantly lower than those of the control group (P=0.00).</span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Conclusion</span></i></b><i><span style="color:blue">:</span></i> Complete revascularization + cardiac rehabilitation intervention can effectively improve patients&#39; 6-min walking test level, improve patients&#39; cardiac function indexes, improve patients&#39; quality of life, improve patients&#39; laboratory index levels, and play a significant role in improving patients&#39; prognosis, which is worthy of widespread promotion.</span></span></span><br> &nbsp; Coronary multibranch lesions, revascularization, cardiac rehabilitation 52 58 http://caspjim.com/browse.php?a_code=A-10-3683-1&slc_lang=en&sid=1 Shengwei Ding bsding0931@126.com 100319475328460055780 0009-0007-3605-4552 No Department of Cardiology, Huai'an Rehabilitation Hospital (Jinhu County People's Hospital), Huaian City, China Chenfeng Ji 23476434@qq.com 100319475328460055781 100319475328460055781 No Department of Cardiology, Huai'an Rehabilitation Hospital (Jinhu County People's Hospital), Huaian City, China Zilong Liu 418543756@qq.com 100319475328460055782 100319475328460055782 No Department of Cardiology, Huai'an Rehabilitation Hospital (Jinhu County People's Hospital), Huaian City, China Hui Zhang 872584242@qq.com 100319475328460055783 100319475328460055783 No Department of Cardiology, Huai'an Rehabilitation Hospital (Jinhu County People's Hospital), Huaian City, China Chunming Tian 1784086026@qq.com 100319475328460055784 100319475328460055784 No Department of Cardiology, Huai'an Rehabilitation Hospital (Jinhu County People's Hospital), Huaian City, China Chen Wang jsjhcardiology@aliyun.com 100319475328460055785 0009-0002-2604-9358 Yes Department of Cardiology, Huai'an Rehabilitation Hospital (Jinhu County People's Hospital), Huaian City, China