en Hematology Hematology Original Article Original Article <p style="text-align:justify"><span style="font-size:14px;"><span style="font-family:Times New Roman;"><span style="line-height:14.4pt"><b><i><span style="color:blue">Background</span></i></b><i><span style="color:blue">:</span></i> Nutritional support is a critical consideration in the care of individuals undergoing hematopoietic stem cell transplantation (HSCT), given the metabolic alterations induced by intensive treatments. This study aimed to explore the correlation between nutritional status and the time to engraftment in HSCT patients at Dr. Kariadi General Hospital, Semarang, Indonesia.</span><br> <span style="line-height:14.4pt"><b><i><span style="color:blue">Methods:</span></i></b> <span style="color:black">This study included adult patients with malignant diseases who underwent autologous or allogeneic HSCT at Dr. Kariadi General Hospital between 2013 and 2023. Nutritional status was evaluated using body mass index (BMI), energy intake, and the type and duration of nutritional support. Neutrophil and platelet engraftment were defined as the time to sustained absolute neutrophil count (ANC) &ge;500 cells/mm&sup3; and platelet count &ge;20 &times; 10⁹/L, respectively, and correlations between numerical variables were analyzed using Pearson&rsquo;s test.</span></span><br> <span style="line-height:14.4pt"><b><i><span style="color:blue">Results:</span></i></b> A total of 45 HSCT patients were involved in this study. There was a significant negative correlation between nutritional intake and neutrophil engraftment (r = -0.776, p <0.001) and platelet engraftment (r= -0.72, P = 0.00), indicating that as the engraftment time increased, nutritional intake decreased. Furthermore, a positive but weak correlation (r = 0.24, P = 0.10) was found between BMI and time to engraftment.</span><br> <span style="line-height:14.4pt"><b><i><span style="color:blue">Conclusion</span></i></b><i><span style="color:blue">:</span></i> <span style="color:black">The study highlights that nutritional status significantly influences engraftment time in HSCT patients, supporting the importance of comprehensive nutritional support to improve outcomes and shorten engraftment.</span><span style="color:#ee0000"></span></span></span></span><br> &nbsp;</p> hematopoietic stem cell transplantation, nutritional status, engraftment time, body mass index, energy intake. 152 157 http://caspjim.com/browse.php?a_code=A-10-3310-2&slc_lang=en&sid=1 Damai Santosa santosaivha@fkundip.ac.id 100319475328460055825 100319475328460055825 Yes Division of Hematology and Medical Oncology, Department of Internal Medicine, Faculty of Medicine, Diponegoro University/Dr. Kariadi General Hospital, Semarang, Indonesia. Daniel Rizky danielrizky@hotmail.co.id 100319475328460055826 100319475328460055826 No Division of Hematology and Medical Oncology, Department of Internal Medicine, Faculty of Medicine, Diponegoro University/Dr. Kariadi General Hospital, Semarang, Indonesia. Kevin Tandarto tandartok@gmail.com 100319475328460055827 100319475328460055827 No Department of Internal Medicine, Faculty of Medicine, Diponegoro University/Dr. Kariadi General Hospital, Semarang, Indonesia. Ika Kartiyani ikakartiyani@gmail.com 100319475328460055828 100319475328460055828 No Division of Hematology and Medical Oncology, Department of Internal Medicine, Faculty of Medicine, Diponegoro University/Dr. Kariadi General Hospital, Semarang, Indonesia. Vina Yunarvika annualmeetingapbmt2023@gmail.com 100319475328460055829 100319475328460055829 No Division of Hematology and Medical Oncology, Department of Internal Medicine, Faculty of Medicine, Diponegoro University/Dr. Kariadi General Hospital, Semarang, Indonesia. Desta Nur Ewika Ardini ardini853@gmail.com 100319475328460055830 100319475328460055830 No Division of Hematology and Medical Oncology, Department of Internal Medicine, Faculty of Medicine, Diponegoro University/Dr. Kariadi General Hospital, Semarang, Indonesia. Budi Setiawan boedhi_73@gmail.com 100319475328460055831 100319475328460055831 No Division of Hematology and Medical Oncology, Department of Internal Medicine, Faculty of Medicine, Diponegoro University/Dr. Kariadi General Hospital, Semarang, Indonesia. Eko Pangarsa ekopangarsa90@gmail.com 100319475328460055832 100319475328460055832 No Division of Hematology and Medical Oncology, Department of Internal Medicine, Faculty of Medicine, Diponegoro University/Dr. Kariadi General Hospital, Semarang, Indonesia. Catharina Suharti hemasemarang@gmail.com 100319475328460055833 100319475328460055833 No Division of Hematology and Medical Oncology, Department of Internal Medicine, Faculty of Medicine, Diponegoro University/Dr. Kariadi General Hospital, Semarang, Indonesia.