en Internal Internal case report case report <p dir="ltr" style="text-align: justify;"><span style="font-size: 12px;"><span style="font-family: times new roman,times,serif;"><strong><em><span style="color: blue;">Background: </span></em></strong>Deep vein thrombosis is an important cause of morbidity and mortality. However, its association with adenomatous polyposis coli is extremely rare. Here we present an interesting case of deep vein thrombosis associated with adenomatous polyposis coli.</span></span></p> <p dir="ltr" style="text-align: justify;"><span style="font-size: 12px;"><span style="font-family: times new roman,times,serif;"><strong><em><span style="color: blue;">Case Presentation:</span></em></strong> A 15 year old female who was having fever and diarrhea for 5 months developed bilateral asymmetric painful swelling of lower limbs for 1 month. Doppler ultrasound of lower limbs revealed presence of thrombosis from inferior vena cava up to popliteal vein. Colonoscopy and biopsy were suggestive of adenomatous polyposis coli. However, she could not tolerate anticoagulant therapy and was put on aspirin therapy for 6 months to which she responded well with the resolution of thrombus.</span></span></p> <p dir="ltr" style="text-align: justify;"><span style="font-size: 12px;"><span style="font-family: times new roman,times,serif;"><strong><em><span style="color: blue;">Conclusion:</span></em></strong> Role of aspirin therapy may be considered whenever a patient of venous thrombosis cannot tolerate anticoagulant therapy</span></span></p> Deep vein thrombosis, Adenomatous polyposis coli, Diarrhea, Aspirin 142 145 http://caspjim.com/browse.php?a_code=A-10-367-1&slc_lang=en&sid=1 Neha Agrawal dr.nagrawal27@gmail.com 10031947532846005300 10031947532846005300 No Department of Medicine, Calcutta National Medical College and Hospital, Kolkata, India Tuhin Santra dralka.y@gmail.com 10031947532846005301 10031947532846005301 Yes Department of Medicine, Calcutta National Medical College and Hospital, Kolkata, India Arnab Kar mearnabkar@gmail.com 10031947532846005302 10031947532846005302 No . Department of Medicine, Gangarampur Subdivisional Hospital, India Pradipta Guha dr.pradipta@yahoo.co.in 10031947532846005303 10031947532846005303 No Department of Medicine, Calcutta National Medical College and Hospital, Kolkata, India Mita Bar mita.bar.87@gmail.com 10031947532846005304 10031947532846005304 No Calcutta National Medical College Apu Adhikary apuadipta@gmail.com 10031947532846005305 10031947532846005305 No Department of Medicine, North Bengal Medical College & Hospital, India Sumana Datta mesumanadatta@gmail.com 10031947532846005306 10031947532846005306 No Department of Family Medicine, Calcutta Medical Research Institute, Kolkata, India