en Neurology Neurology case report case report <span style="font-size:14px;"><span style="font-family:times new roman;"><span style="color:#0000FF;"><strong><em>Background:</em></strong></span> The association of limb-girdle muscular dystrophy (LGMD) with other neurological disorders is uncommon.<br> <span style="color:#0000FF;"><strong><em>Case presentation:</em></strong></span> We report a 25-year-old female with LGMD who suffered from slowly progressive proximal muscular weakness and atrophy since she was 12 years of age. The patient recently presented with acute loss of left side visual acuity. After evaluation, findings were suggestive of multiple sclerosis.<br> <span style="color:#0000FF;"><strong><em>Conclusions:</em> </strong></span>This is the first report of LGMD in association with MS. The simultaneous occurrence of MS with myopathies may be incidental but there may be a genetic susceptibility for both diseases. This comorbidity may influence the treatment of MS</span></span><p></p> Limb-Girdle Muscular Dystrophy, Multiple Sclerosis, Myopathy 96 99 http://caspjim.com/browse.php?a_code=A-10-646-1&slc_lang=en&sid=1 Mahsa Arzani mahsaarzani@gmail.com 100319475328460011204 100319475328460011204 No Department of Neurology, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran. Hamed Rezaei hamed109@gmail.com 100319475328460011205 100319475328460011205 No Department of Urology, Sina Hospital, Tehran University of Medical Sciences; Tehran; Iran Abdorreza Naser Moghadasi abdorrezamoghadasi@gmail.com 100319475328460011206 100319475328460011206 Yes Sina MS Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran