Caspian Journal of Internal Medicine
Babol University of Medical Sciences
دوشنبه 26 شهریور 1403
[Archive]
دوره 13، شماره 3 - ( 3-1401 )
جلد 13 شماره 3 صفحات 554-546 |
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Alvandipour M, Karami M Y, Azadfar M, YazdaniCharati J. Inter sphincter rectal resection with and without malone antegrade continence enema in patients with low rectal cancer: A randomized, prospective, single-blind, parallel clinical trial. Caspian J Intern Med 2022; 13 (3) :546-554
URL: http://caspjim.com/article-1-2305-fa.html
URL: http://caspjim.com/article-1-2305-fa.html
Inter sphincter rectal resection with and without malone antegrade continence enema in patients with low rectal cancer: A randomized, prospective, single-blind, parallel clinical trial. . 1401; 13 (3) :546-554
چکیده: (1788 مشاهده)
Background: Fecal incontinence is the main morbidity of inter-sphincteric resection (ISR) in ultra-low rectal cancer. Malone Ante grade Continence Enema (MACE) has been proposed for these patients. We aimed to compare the quality of life outcomes in cases with ultra-low rectal cancer who had undergone ISR±MACE.
Methods: The current randomized clinical study was accomplished for two years from December 2016 to February 2018 in Imam Khomeini Hospital (Sari City, I.R.Iran) on 30 patients (15 in each group) with rectal cancer. The inclusion criteria of the study were stage 1 and 2a of low rectal cancer with type 2 and 3 of Rullier's classification, those who received neoadjuvant chemo radiotherapy. The exclusion criteria were comorbidity diseases, immune deficiency, poor follow-up. The follow-up period was one year. The Quality of Life (Qol) was reported as primary endpoint. The EORTC QLQ-C30 score and Wexner questionnaires were used. SPSS Version 22 was used. A p-value less than 0.05 was considered statistically significant.
Results: The mean age of patients was 56.23±
Conclusion: Patients who underwent ISR plus MACE surgery had better defecation control and better quality of life than patients without MACE.
Methods: The current randomized clinical study was accomplished for two years from December 2016 to February 2018 in Imam Khomeini Hospital (Sari City, I.R.Iran) on 30 patients (15 in each group) with rectal cancer. The inclusion criteria of the study were stage 1 and 2a of low rectal cancer with type 2 and 3 of Rullier's classification, those who received neoadjuvant chemo radiotherapy. The exclusion criteria were comorbidity diseases, immune deficiency, poor follow-up. The follow-up period was one year. The Quality of Life (Qol) was reported as primary endpoint. The EORTC QLQ-C30 score and Wexner questionnaires were used. SPSS Version 22 was used. A p-value less than 0.05 was considered statistically significant.
Results: The mean age of patients was 56.23±
Conclusion: Patients who underwent ISR plus MACE surgery had better defecation control and better quality of life than patients without MACE.
نوع مطالعه: Original Article |
موضوع مقاله:
Oncology
دریافت: 1399/2/15 | پذیرش: 1400/9/13 | انتشار: 1401/3/11
دریافت: 1399/2/15 | پذیرش: 1400/9/13 | انتشار: 1401/3/11
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