Caspian Journal of Internal Medicine
Babol University of Medical Sciences
چهارشنبه 6 خرداد 1405
[Archive]
دوره 17، شماره 2 - ( 1-1405 )
جلد 17 شماره 2 صفحات 0-13 |
برگشت به فهرست نسخه ها
Ethics code: IR.SUMS.REC.1400.648
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Zangouri V, Molanorouzi M, Ebrahimian S. Investigating Survival of Gastric Cancer Patients with Neoadjuvant Chemotherapy versus Direct Surgery. Caspian J Intern Med 2026; 17 (2) :13-0
URL: http://caspjim.com/article-1-4783-fa.html
URL: http://caspjim.com/article-1-4783-fa.html
Investigating Survival of Gastric Cancer Patients with Neoadjuvant Chemotherapy versus Direct Surgery. . 1405; 17 (2) :13-0
چکیده: (68 مشاهده)
Background: This paper aims to compare Survival of gastric cancer patients with neoadjuvant chemotherapy versus direct surgery. The present research assesses the 36-month survival of gastric cancer patients treated in our center with and without NAC and overall 36-month survival.
Methods: The present research assesses the 36-month survival of gastric cancer patients treated in our center with and without NAC and overall 36-month survival. 79 patients entered this study, of whom 64 received NAC and 15 underwent direct surgery.
Results: Generally, the three-year survival rate in the groups was statistically different based on the Wilcoxon test (P 0.004). NAC was effective in increasing survival in the groups with Lymph o vascular invasion, higher stage and all pathologic groups. However, age, type of surgery (TG vs DG), number of positive lymph nodes, and positive margin after surgery were not effective in interfering with survival in both groups. Neoadjuvant chemotherapy can positively increase OS and DFS in locally advanced gastric cancer. NAC was effective in increasing survival in the groups with Lymph o vascular invasion, higher stage and all pathologic groups.
Conclusion: Considering the similar results in previous studies, larger prospective studies with accurate information can effectively achieve definitive results. However, age, type of surgery (TG vs DG), number of positive lymph nodes, positive margin after surgery were not effective interfering with survival in both groups.
Methods: The present research assesses the 36-month survival of gastric cancer patients treated in our center with and without NAC and overall 36-month survival. 79 patients entered this study, of whom 64 received NAC and 15 underwent direct surgery.
Results: Generally, the three-year survival rate in the groups was statistically different based on the Wilcoxon test (P 0.004). NAC was effective in increasing survival in the groups with Lymph o vascular invasion, higher stage and all pathologic groups. However, age, type of surgery (TG vs DG), number of positive lymph nodes, and positive margin after surgery were not effective in interfering with survival in both groups. Neoadjuvant chemotherapy can positively increase OS and DFS in locally advanced gastric cancer. NAC was effective in increasing survival in the groups with Lymph o vascular invasion, higher stage and all pathologic groups.
Conclusion: Considering the similar results in previous studies, larger prospective studies with accurate information can effectively achieve definitive results. However, age, type of surgery (TG vs DG), number of positive lymph nodes, positive margin after surgery were not effective interfering with survival in both groups.
نوع مطالعه: Original Article |
موضوع مقاله:
Gastroentrology
دریافت: 1404/3/4 | پذیرش: 1404/6/16 | انتشار: 1405/1/4
دریافت: 1404/3/4 | پذیرش: 1404/6/16 | انتشار: 1405/1/4
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