Caspian Journal of Internal Medicine

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Obesity is one of the health problems in the developing and developed countries. Obesity subjects the individuals with metabolic and endocrine disorders. It is obvious that vitamin D deficiency or insufficiency may lead to secondary hyperparathyroidism. Thus, obesity increases the risk of vitamin D deficiency. Considering the high prevalence of vitamin D deficiency in children and adolescents with overweight or obesity, it seems logical to have treatment and prevention from vitamin D deficiency. This is similar to a study in adult vitamin D deficiency related with adiposity which also demonstrates the importance of vitamin D deficiency screening in children and adolescent obesity. Vitamin D replacement can reduce many complications in childhood (skeletal disorder, secondary hyperparathyroidism) and decreases metabolic disorder and cardiovascular disease incidence in later childhood. On the other hand, calcium has a key role in weight regulation, useful in replacement therapy, but there is a need for a further study to reveal exactly the effects in children obesity or overweight.

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