Caspian Journal of Internal Medicine
Babol University of Medical Sciences
Fri, Nov 29, 2024
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Volume 9, Issue 2 (1-2018)
Caspian J Intern Med 2018, 9(2): 140-143 |
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Vakili-sadeghi M, Sedaghat S. Is 99m Tc-methylene diphosphonate bone scintigraphy a sensitive method for detecting bone lesions in multiple myeloma?. Caspian J Intern Med 2018; 9 (2) :140-143
URL: http://caspjim.com/article-1-1014-en.html
URL: http://caspjim.com/article-1-1014-en.html
Babol university of medical sciences2. Cancer Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran , mvakili89@gmail.com
Abstract: (6246 Views)
Background: Bone lesion in multiple myeloma (MM) is most commonly presented as a lytic lesion in this disease. Determination of extent of bone lesions in MM is necessary to follow-up the patients. Whole body bone scan with 99m, Tc-methylene diphosphonate (MDP) has a lower sensitivity than other modalities.
Methods: From the patients with MM admitted to Ayatollah Rouhani Hospital of Babol-Iran from 2009 to 2015, who had undergone whole body bone scan during diagnostic process, were entered into the study. Findings of bone scan were compared with MRI.
Results: Of the 19 patients, sixteen (84.2%) of them had positive finding in bone scan, fifteen (78.9%) had MRI of the spine. While of the thirteen patients who had positive finding in MRI, seven (53.8%) had more positive finding in thorcolumbosacral MRI than in bone scan.
Conclusions: 99m-Tc MDP bone scan is a sensitive but insufficient method for detecting bone lesions in MM.
Methods: From the patients with MM admitted to Ayatollah Rouhani Hospital of Babol-Iran from 2009 to 2015, who had undergone whole body bone scan during diagnostic process, were entered into the study. Findings of bone scan were compared with MRI.
Results: Of the 19 patients, sixteen (84.2%) of them had positive finding in bone scan, fifteen (78.9%) had MRI of the spine. While of the thirteen patients who had positive finding in MRI, seven (53.8%) had more positive finding in thorcolumbosacral MRI than in bone scan.
Conclusions: 99m-Tc MDP bone scan is a sensitive but insufficient method for detecting bone lesions in MM.
Type of Study: Original Article |
Subject:
Hematology
Received: 2017/04/6 | Accepted: 2017/07/18 | Published: 2018/01/8
Received: 2017/04/6 | Accepted: 2017/07/18 | Published: 2018/01/8
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