[صفحه اصلی ]   [Archive]  
:: صفحه اصلي :: درباره نشريه :: آخرين شماره :: تمام شماره‌ها :: جستجو :: ثبت نام :: ارسال مقاله :: تماس با ما ::
:: دوره 11، شماره 1 - ( 11-1398 ) ::
جلد 11 شماره 1 صفحات 1-11 برگشت به فهرست نسخه ها
A systematic review and meta-analysis on the association of serum and tumor tissue iron and risk of breast cancer
چکیده:   (848 مشاهده)
Background: Some studies have investigated the effects of iron on breast carcinogenesis and reported different findings about the association between Fe and breast cancer risk. This study was conducted to estimate this effect using meta-analysis method.
Methods: A total of 20 articles published between 1984 and 2017 worldwide were selected through searching PubMed, Scopus, Embase, Web of Science, and Cochrane Library. Keywords such Breast Cancer, Neoplasm, Trace elements, Iron, Breast tissue concentration, Plasma concentration, Scalp hair concentration, toenail concentration and their combination were used in the search.
Results: The total number of participants was 4,110 individuals comprising 1,624 patients with breast cancer and 2,486 healthy subjects. Fe concentration was measured in the various subgroups in both case and control groups. There were significant correlations between Fe concentration and breast cancer in breast tissue subgroup (SMD: 0.67 [95% CI: 0.17 to 1.17; P=0.009]). Whereas, there was no meaningful difference in Fe status between women with and without breast cancer related to scalp hair and plasma subgroups; (SMD: -3.74 [95% CI: -7.58 to 0.10; P=0.056] and (SMD:-1.14[95% CI: -2.30 to 0.03; P=0.055], respectively.
Conclusion: The present meta-analysis indicated a positive and straight association between iron concentrations and risk of breast cancer but because of high heterogeneity we recommend more accurate future studies
متن کامل [PDF 552 kb]   (196 دریافت)    
نوع مطالعه: Review Article | موضوع مقاله: Oncology
دریافت: ۱۳۹۷/۹/۹ | پذیرش: ۱۳۹۸/۳/۵ | انتشار: ۱۳۹۸/۹/۲۴
ارسال نظر درباره این مقاله
نام کاربری یا پست الکترونیک شما:

CAPTCHA



XML   English Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Sanagoo A, Kiani F, Saei Gharenaz M, Sayehmiri F, koohi F, Jouybari L et al . A systematic review and meta-analysis on the association of serum and tumor tissue iron and risk of breast cancer. Caspian J Intern Med. 2020; 11 (1) :1-11
URL: http://caspjim.com/article-1-1674-fa.html

A systematic review and meta-analysis on the association of serum and tumor tissue iron and risk of breast cancer. 1. 1398; 11 (1) :1-11

URL: http://caspjim.com/article-1-1674-fa.html



دوره 11، شماره 1 - ( 11-1398 ) برگشت به فهرست نسخه ها
Caspian Journal of Internal Medicine
Persian site map - English site map - Created in 0.06 seconds with 32 queries by YEKTAWEB 4075