[Home ] [Archive]    
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 5, Issue 3 (5-2014) ::
Caspian J Intern Med 2014, 5(3): 143-147 Back to browse issues page
Benefits of using intrathecal Buprenorphine
Seyed Mozaffar Rabiee , Ebrahim Alijanpour , Ali Jabbari , Sara Rostami
MD Golestan University of Medical Sciences , amir_a_78@yahoo.com
Abstract:   (4645 Views)
Background: General anesthesia draw the most commonly used modalities for post cesarean delivery pain relief is systemic administration of opioids, while the administration of small dose of intrathecal opioid during spinal anesthesia can be a possible alternative. The aim of this study was to evaluate the effects of buprenorphine on cesarean section prescribed intrathecally. Methods: In this double blind randomized clinical trial, all scheduled patients for cesarean section under spinal anesthesia were enrolled. The patients were randomly divided into 2 groups. Case group received 65-70mg of 5% lidocaine plus 0.2 ml of buprenorphine while the same amount of 5% lidocaine diluted with 0.2 ml of normal saline was given to the control group. Hemodynamic changes and neonatal APGAR scores (Appearance, Pulse, Grimace, Activity, Respiration) were recorded. Pain score was recorded according to the Visual Analogue Scale. Results: Systolic blood pressure was not significantly different until 45th minutes but diastolic blood pressure showed a significant difference at the 15th and 60th minutes (P-value<0.001). Heart rate changes were significantly different between cases and controls at the initial 5th, 15th and after 60th minutes (P<0.001). Pain-free period was significantly different between the two groups (1.25 h versus 18.73 h) (P<0.001). Conclusion: The results show that prescription of intratechal bupernorphine prolong the duration of analgesia without any significant considerable side effects.
Keywords: Keywords: Bupernorphine, Intrathecal, Spinal Anesthesia, post operation pain, Visual analogue scale.
Full-Text [PDF 141 kb]   (1197 Downloads)    
Type of Study: Original Article | Subject: Internal
Received: 2014/05/28 | Accepted: 2014/05/28 | Published: 2014/05/28
Send email to the article author

Add your comments about this article
Your username or Email:

Write the security code in the box >


XML     Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Rabiee S M, Alijanpour E, Jabbari A, Rostami S. Benefits of using intrathecal Buprenorphine. Caspian J Intern Med. 2014; 5 (3) :143-147
URL: http://caspjim.com/article-1-321-en.html


Volume 5, Issue 3 (5-2014) Back to browse issues page
Caspian Journal of Internal Medicine
Persian site map - English site map - Created in 0.05 seconds with 31 queries by YEKTAWEB 3638