Volume 16, Issue 3 (Summer 2025)                   Caspian J Intern Med 2025, 16(3): 393-404 | Back to browse issues page

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Cabral M, Graça-Santos L, Ruivo C, Morais J. Cardiovascular involvement in Sweet’s syndrome: a practical review. Caspian J Intern Med 2025; 16 (3) :393-404
URL: http://caspjim.com/article-1-4244-en.html
Cardiovascular involvement in Sweet’s syndrome: a practical review
Margarida Cabral * , Luís Graça-Santos , Catarina Ruivo , Joao Morais
Department of Cardiology, Leiria Hospital Centre, Leiria, Portugal , anamargaridacabral@outlook.pt
Abstract:   (193 Views)
Sweet’s syndrome, also referred to as acute febrile neutrophilic dermatosis, presents a constellation of clinical features including fever, tender erythematous skin lesions, peripheral neutrophilia, and predominant dermal infiltrate of neutrophils. This uncommon condition can manifest through drug-induced mechanisms, as a secondary condition to malignant diseases, or idiopathically. Importantly, extracutaneous manifestations, including cardiovascular involvement such as arteritis, acute myocarditis, or coronary artery disease, frequently contribute to the intricacy of the clinical presentation. Despite its significance, the literature on Sweet’s syndrome with cardiovascular implications remains sparse, leading to ambiguity in clinical management. In this context, we examine the requirement for a heightened index of suspicion to establish a diagnosis of Sweet’s syndrome with concurrent cardiovascular involvement, alongside considerations for treatment modalities and post-diagnostic monitoring strategies.
 
Keywords: Sweet syndrome, arteritis, myocarditis, coronary artery disease
     
Type of Study: Review Article | Subject: Cardiology
Received: 2024/01/12 | Accepted: 2024/03/6 | Published: 2025/06/10
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