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Shahnaz Barat, Sedigheh Esmaeilzadeh, Masoumeh Golsorkhtabaramiri, Soraya Khafri, Maryam Moradi Recabdarkolaee ,
Volume 6, Issue 2 (4-2015)
Abstract

 Background: The early postoperative feeding after caesarean section (C- section) has remained controversial. This study was designed to evaluate the safety and efficacy of early versus delayed postcaesarean section oral feeding regarding gastrointestinal complications and patients postoperative satisfaction after C- section.

 Methods: This clinical trial study was conducted on 200 pregnant women undergoing planned C-section under spinal anesthesia (Registration Number: IRCT: 138712211760N1). Women were randomly divided in two groups group A (early feeding group) comprised of 101 patients who were encouraged to take oral fluid. If they tolerated, they continue semi-solid and solid foods starting 2 h after caesarean section. Group B (delayed feeding group) comprised of 99 patients who were given oral fluid 8 h after surgery. After beginning of feeding the patients’ tolerance, first flatus, first defecation, beginning of regular diet, the length of hospital stay and also patient satisfaction level were evaluated in each group by visual scale analog (VAS).

 Results: The mean time of the first passage of flatus was 10.2±1.7 hours for the early oral feeding group versus 10.7±1.6 hours for the delayed feeding group and the difference was significant (P=0.03). Duration to first defecation and length of hospital stay as well as patient satisfaction level did not differ significantly between the two groups.

 Conclusion: The results of this study suggest early postcaesarean feeding. It is well tolerated and helps return normal feeding habits.

 


Maryam Gholinezhad , Masoumeh Golsorkhtabaramiri, Sedighe Esmaeilzadeh, Azita Ghanbarpour ,
Volume 9, Issue 3 (5-2018)
Abstract

Background: Polycystic ovary syndrome (PCOs) is an endocrine-metabolic disorder. This study intends to determine the comparison of insulin resistance (IR) and metabolic disturbance in overweight/obese and normal-weight of young women with polycystic ovary syndrome.
Methods: Using a comparative cross-sectional study design in 2015, 27 normal weight (18 Results: 112 women with PCOS participated in this study. The mean age was 22.4±3.48 years in the normal PCOS group (n=27) and 24.4±5.06 years in the overweight/obese PCOS patients (n=85). BMI had a significant straight correlation with insulin resistance (p<0.001) and a negative correlation with insulin sensitivity (p<0.001). BMI showed a straight stronger correlation with triglyceride (TG) (p<0.001) and LDL cholesterol (<0.05) and a stronger reverse relationship with SHBG (p<0.001). In overweight/obese group, 91.7% (48) of the women showed insulin resistance (HOMA>3.15) vs. 8.3% (5) in the normal group (P<0.001). 82.4% (62) of the overweight/obese group revealed low insulin sensitivity (QUICKI<0.34) while this value was 17.6 % (13) within their lean counterparts (p<0.001). In the study group, 89.7 % (54) showed elevated fasting insulin concentration (>13µU/ml) vs. 10.3% (7) in the control group (p<0.001).
Conclusions: Overweight/obese PCOs patients revealed higher insulin resistance and lower insulin sensitivity, and also greater TG and LDL cholesterol. Priority of management of insulin resistance and lipid profile should be considered on identifying these potentially major complications.

 

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