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Is 99m Tc-methylene diphosphonate bone scintigraphy a sensitive method for detecting bone lesions in multiple myeloma?
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چکیده: (5965 مشاهده) |
Background: Bone lesion in multiple myeloma (MM) is most commonly presented as a lytic lesion in this disease. Determination of extent of bone lesions in MM is necessary to follow-up the patients. Whole body bone scan with 99m, Tc-methylene diphosphonate (MDP) has a lower sensitivity than other modalities.
Methods: From the patients with MM admitted to Ayatollah Rouhani Hospital of Babol-Iran from 2009 to 2015, who had undergone whole body bone scan during diagnostic process, were entered into the study. Findings of bone scan were compared with MRI.
Results: Of the 19 patients, sixteen (84.2%) of them had positive finding in bone scan, fifteen (78.9%) had MRI of the spine. While of the thirteen patients who had positive finding in MRI, seven (53.8%) had more positive finding in thorcolumbosacral MRI than in bone scan.
Conclusions: 99m-Tc MDP bone scan is a sensitive but insufficient method for detecting bone lesions in MM.
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متن کامل [PDF 185 kb]
(794 دریافت)
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نوع مطالعه: Original Article |
موضوع مقاله:
Hematology
دریافت: 1396/1/17 | پذیرش: 1396/4/27 | انتشار: 1396/10/18
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