Caspian Journal of Internal Medicine
Babol University of Medical Sciences
یکشنبه 21 اردیبهشت 1404
[Archive]
دوره 2، شماره 3 - ( 10-1389 )
جلد 2 شماره 3 صفحات 269-266 |
برگشت به فهرست نسخه ها
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Qujeq D, Sadogh M, Savadkohi S. Association between helicobacter pylori infection and serum iron profile. Caspian J Intern Med 2011; 2 (3) :266-269
URL: http://caspjim.com/article-1-118-fa.html
URL: http://caspjim.com/article-1-118-fa.html
Association between helicobacter pylori infection and serum iron profile. . 1389; 2 (3) :266-269
چکیده: (9336 مشاهده)
Background: It is clear that Helicobacter pylori (H. pylori) is a spiral bacterium that infects human and causes gastritis and peptic ulcer. The aim of this study was to determine the relationship between H .pylori infection and the iron status of the body.
Methods: This study was conducted in Shahid Beheshti Hospital of Babol University of Medical Sciences, Babol, Iran from August 2007 to July 2008. The study group consisted of 35 patients with H. pylori and 35 matched healthy subjects as the control group. The members of both groups were enrolled in the study voluntarily. Serum iron and total iron- binding capacity were measured by Darman-kav Standard kit. Ferritin was measured by Padtan-e-Elm Standard kit. The Collected data were analyzed by SPSS version 16. p-value of <0.05 was considered significant.
Results: The serum iron and total iron-binding capacity in H. pylori positive group were lower than in the control group (108.67±31.26 vs. 110.92±28.45 µg/dL, p=0.578) and (327.88±81.39 vs. 342.51±79.45 µg/dL, p=0.153) respectively. The mean of ferritin was significantly lower in H.pylori positive group (210.51±132.01 ng/ml, p=0.047) than H.pylori negative group (265.03±170.79 ng/mL, p=0.047).
Conclusion: The results of the present study show that serum iron and total iron binding capacity in H.pylori infected group was lower than the control group. H.pylori may impair iron metabolism. It is possible that H.pylori may both directly compete with the host for available iron by impairing its uptake.
Methods: This study was conducted in Shahid Beheshti Hospital of Babol University of Medical Sciences, Babol, Iran from August 2007 to July 2008. The study group consisted of 35 patients with H. pylori and 35 matched healthy subjects as the control group. The members of both groups were enrolled in the study voluntarily. Serum iron and total iron- binding capacity were measured by Darman-kav Standard kit. Ferritin was measured by Padtan-e-Elm Standard kit. The Collected data were analyzed by SPSS version 16. p-value of <0.05 was considered significant.
Results: The serum iron and total iron-binding capacity in H. pylori positive group were lower than in the control group (108.67±31.26 vs. 110.92±28.45 µg/dL, p=0.578) and (327.88±81.39 vs. 342.51±79.45 µg/dL, p=0.153) respectively. The mean of ferritin was significantly lower in H.pylori positive group (210.51±132.01 ng/ml, p=0.047) than H.pylori negative group (265.03±170.79 ng/mL, p=0.047).
Conclusion: The results of the present study show that serum iron and total iron binding capacity in H.pylori infected group was lower than the control group. H.pylori may impair iron metabolism. It is possible that H.pylori may both directly compete with the host for available iron by impairing its uptake.
نوع مطالعه: Original Article |
موضوع مقاله:
Infectious Diseases
دریافت: 1392/10/25 | پذیرش: 1392/10/25 | انتشار: 1392/10/25
دریافت: 1392/10/25 | پذیرش: 1392/10/25 | انتشار: 1392/10/25
| بازنشر اطلاعات | |
 |
این مقاله تحت شرایط Creative Commons Attribution-NonCommercial 4.0 International License قابل بازنشر است. |
