Caspian Journal of Internal Medicine
Babol University of Medical Sciences
پنجشنبه 13 دی 1403
[Archive]
دوره 14، شماره 3 - ( 2-1402 )
جلد 14 شماره 3 صفحات 589-586 |
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Solouki A, Manoochehrabadi T, Korani F, Farshchi M. Reporting two hemoglobin J Iran cases, molecular follow-up, or is it insignificant?. Caspian J Intern Med 2023; 14 (3) :586-589
URL: http://caspjim.com/article-1-3334-fa.html
URL: http://caspjim.com/article-1-3334-fa.html
Reporting two hemoglobin J Iran cases, molecular follow-up, or is it insignificant?. . 1402; 14 (3) :586-589
چکیده: (1516 مشاهده)
Background: Hemoglobin J is one of the fast hemoglobin that has a more negative charge due to β77His→Asp substitution. Acquisition of this hemoglobin is not associated with any specific clinical sign, but the combination of this hemoglobinopathy with beta-thalassemia and other hemoglobinopathies can cause challenges.
Case Presentation: In this article, two cases with hemoglobin J are introduced; the first patient for premarital testing and the other for his fatigue. The hemoglobin electrophoresis was done by Sebia capillary zone electrophoresis and Hb J as heterozygote and homozygote were determined.
Conclusion: It must be noted that although this hemoglobinopathy is not related to any problem alone but could be confusing in combination with other hemoglobinopathies or thalassemia. In this paper, these two cases are introduced and an attempt was made to investigate the importance of molecular follow-up.
Case Presentation: In this article, two cases with hemoglobin J are introduced; the first patient for premarital testing and the other for his fatigue. The hemoglobin electrophoresis was done by Sebia capillary zone electrophoresis and Hb J as heterozygote and homozygote were determined.
Conclusion: It must be noted that although this hemoglobinopathy is not related to any problem alone but could be confusing in combination with other hemoglobinopathies or thalassemia. In this paper, these two cases are introduced and an attempt was made to investigate the importance of molecular follow-up.
نوع مطالعه: case report |
موضوع مقاله:
Hematology
دریافت: 1400/11/2 | پذیرش: 1401/3/18 | انتشار: 1402/3/8
دریافت: 1400/11/2 | پذیرش: 1401/3/18 | انتشار: 1402/3/8
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