Caspian Journal of Internal Medicine
Babol University of Medical Sciences
پنجشنبه 13 دی 1403
[Archive]
دوره 16، شماره 1 - ( 7-1404 )
جلد 16 شماره 1 صفحات 57-47 |
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Faramarzpour M, Mohammad Hosseiniazar M, Hooshmand Gharabagh L. Assessment of Relationship between Non-alcoholic Fatty Liver Disease and LV Diastolic Dysfunction in Patients with Type 2 Diabetes Mellitus. Caspian J Intern Med 2025; 16 (1) :47-57
URL: http://caspjim.com/article-1-4102-fa.html
URL: http://caspjim.com/article-1-4102-fa.html
Assessment of Relationship between Non-alcoholic Fatty Liver Disease and LV Diastolic Dysfunction in Patients with Type 2 Diabetes Mellitus. . 1404; 16 (1) :47-57
چکیده: (559 مشاهده)
Background: To date, the clinical implications of the long-lasting non-alcoholic fatty liver disease (NAFLD) such as the left ventricular diastolic dysfunction (LVDD) in the course of type 2 diabetes mellitus (T2DM) are yet to be determined. The main aim of this study was to investigate the correlation between NAFLD and early LVDD progression along with demographic characteristics.
Methods: This cross-sectional study was performed on ninety consecutive diabetic outpatients referred to the endocrinology clinic. Demographic data were collected using a designed checklist. Ultrasound imaging was performed to assess the fatty liver condition. To assess LV diastolic function, echocardiography was performed, using a trans-thoracic tissue Doppler echocardiography.
Results: The results showed that the majority of participants were females (61.1%). The fasting blood glucose (FBG, mg/dl) level was 174.65 ±51.1. Also, the mean body mass index (BMI) was 28.92±4.19, which was significantly associated with NAFLD. It has been also estimated that 76.7% and 81.1% of diabetic patients had NAFLD and simultaneous LVDD, respectively. However, the statistical results did not show a significant association between non-progressive NAFLD and LVDD (p<0.05).
Conclusion: There was no correlation between NAFLD and LVDD progression. However, timely evaluation of LVDD in T2DM outpatients with NAFLD can strongly help to prevent possible cardiomyopathy in high-risk populations.
Methods: This cross-sectional study was performed on ninety consecutive diabetic outpatients referred to the endocrinology clinic. Demographic data were collected using a designed checklist. Ultrasound imaging was performed to assess the fatty liver condition. To assess LV diastolic function, echocardiography was performed, using a trans-thoracic tissue Doppler echocardiography.
Results: The results showed that the majority of participants were females (61.1%). The fasting blood glucose (FBG, mg/dl) level was 174.65 ±51.1. Also, the mean body mass index (BMI) was 28.92±4.19, which was significantly associated with NAFLD. It has been also estimated that 76.7% and 81.1% of diabetic patients had NAFLD and simultaneous LVDD, respectively. However, the statistical results did not show a significant association between non-progressive NAFLD and LVDD (p<0.05).
Conclusion: There was no correlation between NAFLD and LVDD progression. However, timely evaluation of LVDD in T2DM outpatients with NAFLD can strongly help to prevent possible cardiomyopathy in high-risk populations.
نوع مطالعه: Original Article |
موضوع مقاله:
Internal
دریافت: 1402/7/10 | پذیرش: 1402/10/23 | انتشار: 1404/8/4
دریافت: 1402/7/10 | پذیرش: 1402/10/23 | انتشار: 1404/8/4
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