Isolated thrombocytopenia report of a rare presentation of childhood Systemic Lupus Erythematosus
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چکیده: (8746 مشاهده) |
Background: Systemic lupus erythematosus (SLE) has various
presentations in children. Hematologic abnormalities is common in childhood onset
of SLE, however, isolated thrombocytopenia is relatively rare. Thus, we present
a child with isolated thrombocytopenia as a rare presentation of SLE. Case presentation: A 12-year-old boy with chief
complaints of loss of appetite, weight loss, decreased platelet count (8000/µL)
and lymph node enlargement was referred to our hospital. Biopsy of lymph node
showed reactive lymphadenopathy. Investigations regarding infectious disease
was negative. Platelet count remained low after low dose steroidned therapy.
Antinuclear antibody (ANA) and anti-double stranded DNA antibody screening
tests were positive with titer of 1/62 and 1/54, respectively. Therefore,
juvenile SLE was considered as the final diagnosis and raising the dose of
prednisolone to 2mg/kg/day was associated with increasing platelet count to 40000/µL
and a week later to 96000/µL. Conclusion: The findings of this study indicate that in cases with
isolated thrombocytopenia refractory to conventional dose of steroids, SLE
should be considered. This study justifies serum ANA and anti DNA assessment in
children with thrombocytopenia |
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متن کامل [PDF 202 kb]
(2364 دریافت)
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نوع مطالعه: case report |
موضوع مقاله:
Infectious Diseases دریافت: 1392/10/22 | پذیرش: 1393/7/29 | انتشار: 1394/4/1
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