[Home ] [Archive]    
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 9, Issue 3 (5-2018) ::
Caspian J Intern Med 2018, 9(3): 206-210 Back to browse issues page
Cross-talks between the kidneys and the central nervous system in multiple sclerosis
Sahar Rostami , Mohammad Sajad Emami Aleagha , Maryam Ghasemi-Kasman , Abdolamir Allameh
Ph.D Department of Clinical Biochemistry, Faculty of Medicine, Tarbiat Modarres University, Tehran, Iran , allameha@modares.ac.ir
Abstract:   (427 Views)
Multiple sclerosis (MS) is an inflammatory demyelinating disease, which is considered as a common autoimmune disorder in young adults. A growing number of evidences indicated that the impairment in non-neural tissues plays a significant role in pathology of MS disease. There are bidirectional relationship, metabolic activities and functional similarity between central nervous system (CNS) and kidneys which suggest that kidney tissue may exert remarkable effects on some aspects of MS disorder and CNS impairment in these patients compels the kidney to respond to central inflammation. Recently, it has been well documented that hormonal secretion possesses the important role on CNS abnormalities. In this regard, due to the functional similarity and significant hormonal and non-hormonal relationship between CNS and kidneys, we hypothesized that kidneys exert significant effect on initiation, progression or amelioration of MS disease which might be regarded as potential therapeutic approach in the treatment of MS patients in the future.

Keywords: Multiple sclerosis, Kidneys, Central nervous system, Hormones
Full-Text [PDF 209 kb]   (66 Downloads)    
Type of Study: Short Communication | Subject: Neurology
Received: 2017/07/1 | Accepted: 2017/11/26 | Published: 2018/05/7
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA code



XML     Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Rostami S, Emami Aleagha M S, Ghasemi-Kasman M, Allameh A. Cross-talks between the kidneys and the central nervous system in multiple sclerosis. Caspian J Intern Med. 2018; 9 (3) :206-210
URL: http://caspjim.com/article-1-1131-en.html


Volume 9, Issue 3 (5-2018) Back to browse issues page
Caspian Journal of Internal Medicine
Persian site map - English site map - Created in 0.05 seconds with 31 queries by YEKTAWEB 3731