Caspian Journal of Internal Medicine
Babol University of Medical Sciences
چهارشنبه 29 اسفند 1403
[Archive]
دوره 10، شماره 3 - ( 3-1398 )
جلد 10 شماره 3 صفحات 275-271 |
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Kafi G, Akbarpour S, Arefi M, Behnoush B, Ahmadi Pishkuhi M, Barzegari N. Effect of hydroxyethyl starch on acidosis in patients with aluminum phosphide poisoning. Caspian J Intern Med 2019; 10 (3) :271-275
URL: http://caspjim.com/article-1-1594-fa.html
URL: http://caspjim.com/article-1-1594-fa.html
Effect of hydroxyethyl starch on acidosis in patients with aluminum phosphide poisoning. . 1398; 10 (3) :271-275
چکیده: (4808 مشاهده)
Background: Given the fact that various studies have reported the positive effects of hydroxyethyl starch therapy in controlling shock, this study aimed to compare the effects of hydroxyethyl starch on modifying acidosis and treating patients with aluminum phosphide poisoning.
Methods: This was a randomized clinical trial that was conducted on 60 patients with aluminum phosphide poisoning. We compared the two groups of patients treated with hydroxyethyl starch and normal saline. Base excess and serum pH of arterial blood gases (ABG) were measured before and after the treatment and compared by t-test.
Results: Results showed that arterial pH in the starch group and normal saline group increased by 0.13 and 0.18, respectively, and the difference between the two groups was not statistically significant. The difference in the base excess before and after treatment in the starch group and normal saline group was 6.41 and 5.39, respectively, and the difference between the two groups was not statistically significant. Changes in mean values of arterial pH after the intervention in comparison with before treatment were statistically significant (p<0.05).
Conclusion: Overall, the results of the present study show that starch is at least as effective as normal saline in treating acidosis in patients poisoned with aluminum phosphide and can be used instead of normal saline, and both of the two treatments could be equally effective.
Methods: This was a randomized clinical trial that was conducted on 60 patients with aluminum phosphide poisoning. We compared the two groups of patients treated with hydroxyethyl starch and normal saline. Base excess and serum pH of arterial blood gases (ABG) were measured before and after the treatment and compared by t-test.
Results: Results showed that arterial pH in the starch group and normal saline group increased by 0.13 and 0.18, respectively, and the difference between the two groups was not statistically significant. The difference in the base excess before and after treatment in the starch group and normal saline group was 6.41 and 5.39, respectively, and the difference between the two groups was not statistically significant. Changes in mean values of arterial pH after the intervention in comparison with before treatment were statistically significant (p<0.05).
Conclusion: Overall, the results of the present study show that starch is at least as effective as normal saline in treating acidosis in patients poisoned with aluminum phosphide and can be used instead of normal saline, and both of the two treatments could be equally effective.
نوع مطالعه: Original Article |
موضوع مقاله:
Internal
دریافت: 1397/6/5 | پذیرش: 1397/11/9 | انتشار: 1398/5/5
دریافت: 1397/6/5 | پذیرش: 1397/11/9 | انتشار: 1398/5/5
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