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:: Volume 10, Issue 2 (3-2019) ::
Caspian J Intern Med 2019, 10(2): 197-204 Back to browse issues page
The effectiveness of low trans-fatty acids dietary pattern in pregnancy and the risk of gestational diabetes mellitus
Seideh-Hanieh Alamolhoda , Masoumeh Simbar , Parvin Mirmiran , Parvaneh Mirabi
Infertility and Reproductive Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran , parvaneh_mirabi@yahoo.com
Abstract:   (1736 Views)
Background: Gestational diabetes mellitus (GDM) is a common disorder in pregnancy. The association of trans fatty acids (TFA) intake and risk of GDM have been reported; It remains unclear whether dietary TFA can influence GDM risk. We examined the effect of low TFA dietary intakes during pregnancy on risk of GDM.
Methods: This randomized controlled trial was performed on 800 pregnant women who were randomly divided into 393 intervention and 407 comparison groups with gestational age 7 weeks. In the intervention group, the diet of pregnant women was designed in such a way that their daily intake of TFA content was less than1% but in control group, the daily intake of TFA content was not changed. The dietary intake was assessed using a 24-hour dietary recall questionnaire for three non-consecutive days at the beginning of the pregnancy before week 7, and at 13, 25 and 35 weeks. Diagnosis of GDM was performed using a 3-hour glucose tolerance test with 100 g glucose at 24-28 weeks of gestation.
Results: 14 women in the intervention group (5%) and 31 women in the control group (8%) were diagnosed with GDM. Chi-square test did not show any significant difference between two groups (P=0.08). Cox model was used and the variables were examined in four multivariate models that none of the modals showed a statistically significant difference between the two groups regarding the incidence of GDM.
Conclusion: It seems that the diet with low trans-fatty acid content has no effect on the incidence of GDM.
Keywords: Gestational diabetes mellitus, Trans-fatty acids, 24-hour dietary recall
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Type of Study: Original Article | Subject: Nutrition
Received: 2018/11/3 | Accepted: 2018/12/17 | Published: 2019/05/13
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Alamolhoda S, Simbar M, Mirmiran P, mirabi P. The effectiveness of low trans-fatty acids dietary pattern in pregnancy and the risk of gestational diabetes mellitus. Caspian J Intern Med. 2019; 10 (2) :197-204
URL: http://caspjim.com/article-1-1647-en.html

Volume 10, Issue 2 (3-2019) Back to browse issues page
Caspian Journal of Internal Medicine
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