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:: Volume 10, Issue 3 (6-2019) ::
Caspian J Intern Med 2019, 10(3): 320-325 Back to browse issues page
Normal values of neutrophils/lymphocytes ratio, lymphocytes/monocytes ratio and platelets/lymphocytes ratio among Iranian population: Results of Tabari cohort
Mahmood Moosazadeh , Iradj Maleki , Reza Alizadeh-Navaei * , Motahareh Kheradmand , Akbar Hedayatizadeh-Omran , Amir Shamshirian , Agil Barzegar
Gastrointestinal Cancer Research Center, Mazandaran University of Medical Sciences, Sari, Iran , reza_nava@yahoo.com
Abstract:   (477 Views)
Background: Neutrophil-lymphocyte ratio (NLR), lymphocyte-monocyte ratio (LMR) and platelet-lymphocyte ratio (PLR) have a prognostic value in several types of diseases such as cancers and they vary in different races. So, we aimed to evaluate the normal range of these markers among healthy people to determine the normal value in Iranian population.
Methods: In the present study, cross-sectional data of population-based cohort study named “Tabari cohort study” was utilized. In the first phase of Tabari cohort, 10255 participants aged 35-70 years from urban and rural areas of Sari, Mazandaran, Iran entered into the study. The study included a questionnaire survey and blood collection. Blood samples were collected after 12 hours fasting from all participants during the study. Hematological indices were measured for all samples using Celltac Alpha MEK-6510 K (Tokyo, Japan).
Results: After sample exclusion, 2212 healthy subjects of Tabari's normal cohort population were investigated. The mean age of the samples was 47.9±9.29 years. The mean of NLR, LMR, PLR were 1.70±0.70, 11.15±3.14 and 117.05±47.73, respectively.
Conclusion: Our investigation provides preliminary reference values for NLR, LMR, and PMR among Iranian population that can be used for disease progress in various clinical procedures.
Keywords: Normal values, neutrophils-lymphocytes ratio, lymphocytes-monocytes ratio, platelets-lymphocytes ratio
Full-Text [PDF 326 kb]   (77 Downloads)    
Type of Study: Original Article | Subject: Hematology
Received: 2019/01/20 | Accepted: 2019/05/12 | Published: 2019/07/27
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Moosazadeh M, Maleki I, Alizadeh-Navaei R, Kheradmand M, Hedayatizadeh-Omran A, Shamshirian A et al . Normal values of neutrophils/lymphocytes ratio, lymphocytes/monocytes ratio and platelets/lymphocytes ratio among Iranian population: Results of Tabari cohort. Caspian J Intern Med. 2019; 10 (3) :320-325
URL: http://caspjim.com/article-1-1733-en.html


Volume 10, Issue 3 (6-2019) Back to browse issues page
Caspian Journal of Internal Medicine
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