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:: Volume 11, Issue 4 (6-2020) ::
Caspian J Intern Med 2020, 11(4): 398-402 Back to browse issues page
The association of platelet count and mean platelet volume (MPV) index with types of stroke
Bahram Zarmehri , Behzad Shahi , Shaghayegh Rahmani , Fatemeh Dehghan Tafti , Mahdi Foroughian
Department of Emergency Medicine, Faculty of Medicine, Mashhad University of Medical sciences, Mashhad, Iran. , foroughianmh@mums.ac.ir
Abstract:   (648 Views)
Background: Stroke is known to be the third most prominent cause of death in the developing countries and the most common debilitating neurologic disease. This study aimed to investigate the association of platelet count (PC) and mean platelet volume (MPV) index with various stroke types.
Methods: This cross-sectional study was carried out on patients over the age of 18 years who presented with signs and symptoms of the first acute stroke. Exclusion criteria were underlying chronic liver or renal disease and the time more than 6 hours from symptom initiation, hematological and infectious disorders in patients. After recording of demographic data, a complete blood cell count (CBC) test was performed.
Results: From 150 patients, who enrolled in the study, 54.7% of patients were males. The initial brain CT scan was normal in 13 (8.7%) patients and showed evidence of brain infarction and intracranial hemorrhage in 84 (56%) and 53 (35.3%) patients respectively. Patients with intracranial hemorrhage had significantly higher mean of MPV index than the patients with normal brain-CT scan and patients with evidence of brain infarction (p<0.001).
Conclusion: The MVP index can be a predictor of the type of hemorrhagic or ischemic finding in emergency CT scan in stroke patients. This relationship may help to better understand the physiopathologic role of platelets in the development of stroke (hemorrhagic or ischemic), but will not replace cerebral computed tomography to diagnose the type of stroke, or it may not initiate treatment for hemorrhagic stroke.
Keywords: Stroke, Platelet Count, Mean Platelet Volume index
Full-Text [PDF 178 kb]   (104 Downloads)    
Type of Study: Original Article | Subject: Neurology
Received: 2019/07/5 | Accepted: 2020/02/10 | Published: 2017/07/15
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Zarmehri B, shahi B, Rahmani S, Dehghan Tafti F, Foroughian M. The association of platelet count and mean platelet volume (MPV) index with types of stroke. Caspian J Intern Med. 2020; 11 (4) :398-402
URL: http://caspjim.com/article-1-1966-en.html

Volume 11, Issue 4 (6-2020) Back to browse issues page
Caspian Journal of Internal Medicine
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