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:: Volume 12, Issue 3 (4-2021) ::
Caspian J Intern Med 2021, 12(3): 290-293 Back to browse issues page
Added diagnostic value of SPECT to evaluate bone metastases in breast cancer patients with normal whole body bone scan
Seyed Mohammad Abedi, Alireza Mardanshahi * , Reza Zeinali
1. Department of Radiology and Nuclear Medicine , Faculty of Medicine, Cardiovascular Research Center, Mazandaran University of Medical Sciences, Sari, Iran , amardanshahi@yahoo.com
Abstract:   (762 Views)
Background: In this research, we aimed to survey the added value of single photon emission computed tomography (SPECT) in comparison with planar whole body bone scan to visualize bone metastatic lesions in patients with breast cancer.
Methods: A total of 80 patients with breast cancer (invasive ductal carcinoma) were examined with planar whole body bone scan and SPECT imaging using 99mTc-labelled methylene diphosphonate (99mTc-MDP). The patients with abnormal uptakes in SPECT imaging were also investigated with magnetic resonance imaging (MRI).
Results: Among these 80 patients with normal whole body bone SPECT scan, 19 (23.25%) of them revealed abnormal 99mTc-MDP uptake in skeleton. Furthermore, these 19 patients were subjected to MRI and 3 (3.75%) of them were confirmed with metastatic bone lesion.
Conclusion: The obtained data suggest that SPECT possess the added diagnostic over planar whole body bone scan.
Keywords: 99mTc-MDP, SPECT, whole body bone scan, breast cancer, bone metastasis
Full-Text [PDF 153 kb]   (234 Downloads)    
Type of Study: Original Article | Subject: Radiology
Received: 2019/12/7 | Accepted: 2020/10/11 | Published: 2021/04/1
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Abedi S M, Mardanshahi A, Zeinali R. Added diagnostic value of SPECT to evaluate bone metastases in breast cancer patients with normal whole body bone scan. Caspian J Intern Med. 2021; 12 (3) :290-293
URL: http://caspjim.com/article-1-2139-en.html


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Volume 12, Issue 3 (4-2021) Back to browse issues page
Caspian Journal of Internal Medicine
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