Volume 12 - Case Supplement                   Caspian J Intern Med 2021, 12 - Case Supplement : 447-450 | Back to browse issues page


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Eghbali F, Karami R. Refractory hypoglycemia induced by a duodenal wall gastrointestinal stromal tumor: A case report. Caspian J Intern Med 2021; 12 (S2) :447-450
URL: http://caspjim.com/article-1-2227-en.html
Minimally Invasive Surgery Research Center, Iran University of Medical Sciences, Tehran, Iran , reza_karami1367@yahoo.com
Abstract:   (2435 Views)
Background: Tumor-associated hypoglycemia can be caused by non-islet cell tumors including gastrointestinal stromal tumor (GIST) which is a rare paraneoplastic syndrome that leads to the release of insulin-like growth factor-2 (IGF-2).
Case Presentation: We report the case of a 45-year old woman who was admitted to our hospital with refractory hypoglycemic episodes. We found normal serum insulin and c-peptide level and abdominal CT-scan showed a small duodenal wall lesion suggesting insulinoma. After tumor resection, hypoglycemia symptoms were recovered, but the pathological findings demonstrated the lesion was GIST.
Conclusion: In a small gastrointestinal lesion with hypoglycemic symptoms we should consider IGF-II secreting GIST in addition to insulinoma.
Keywords: Hypoglycemia, GIST, IGF-II
Full-Text [PDF 151 kb]   (606 Downloads)    
Type of Study: case report | Subject: Surgery
Received: 2020/02/22 | Accepted: 2020/08/1 | Published: 2021/07/24

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