Caspian Journal of Internal Medicine
Babol University of Medical Sciences
Wed, Mar 19, 2025
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Volume 12, Issue 4 (Autumn 2021)
Caspian J Intern Med 2021, 12(4): 606-612 |
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Yazdanpanah M J, Vahabi-Amlashi S, Nematy M, Shaelaei N, Mohajeri S A R, Tafazzoli Z. The Association of Serum Lipid Profiles and Dietary Intakes of Vitamin E and Fiber with Psoriasis Severity. Caspian J Intern Med 2021; 12 (4) :606-612
URL: http://caspjim.com/article-1-2273-en.html
URL: http://caspjim.com/article-1-2273-en.html
Mohammad Javad Yazdanpanah 
, Sadegh Vahabi-Amlashi , Mohsen Nematy , Neda Shaelaei , Seyed Amir Reza Mohajeri , Zahra Tafazzoli *
, Sadegh Vahabi-Amlashi , Mohsen Nematy , Neda Shaelaei , Seyed Amir Reza Mohajeri , Zahra Tafazzoli *
Cutaneous Leishmaniasis Research Center, Mashhad University of Medical Sciences, Mashhad, Iran , TafazzoliZ951@mums.ac.ir
Abstract: (3716 Views)
Background: Dyslipidemia has been reportedly associated with an increased risk of atherosclerosis among psoriatic patients. Dietary intake can be a key factor in the pathophysiology of psoriasis. Herein, we assessed serum lipid profile and dietary intake in psoriatic patients, in comparison with healthy subjects.
Methods: In this case-control study, 45 psoriatic patients and 43 healthy controls were evaluated. We estimated the macro/micronutrient intakes and energy, using a food frequency questionnaire (FFQ). Anthropometric parameters and serum levels of triglyceride (TG), high-density lipoproteins (HDL), low-density lipoproteins (LDL), and very low-density lipoproteins were assessed. The case group was categorized by severity measured by PASI score (mild<10, moderate 10-20, severe >20). Diet plan 6.0 was used to analyze FFQs and data were analyzed in SPSS 16.0, with p<0.05 considered significant.
Results: The case group had markedly higher body mass index (BMI), LDL, and cholesterol and significantly lower HDL compared with controls (p<0.05). Carbohydrate, energy, fat intakes were significantly higher in cases, while folate, fiber, and vitamin E intakes were significantly lower in the case group, compared with the control group (p<0.05). BMI, cholesterol, and triglyceride values and dietary intakes of fiber and vitamin E were significantly associated with severity of psoriasis (p<0.05).
Conclusion: Serum lipid profile and dietary intake are substantially important in psoriasis severity. Therefore, close monitoring of lipid profile and BMI during admission and follow-up and dietary modification can improve the severity of psoriasis.
Methods: In this case-control study, 45 psoriatic patients and 43 healthy controls were evaluated. We estimated the macro/micronutrient intakes and energy, using a food frequency questionnaire (FFQ). Anthropometric parameters and serum levels of triglyceride (TG), high-density lipoproteins (HDL), low-density lipoproteins (LDL), and very low-density lipoproteins were assessed. The case group was categorized by severity measured by PASI score (mild<10, moderate 10-20, severe >20). Diet plan 6.0 was used to analyze FFQs and data were analyzed in SPSS 16.0, with p<0.05 considered significant.
Results: The case group had markedly higher body mass index (BMI), LDL, and cholesterol and significantly lower HDL compared with controls (p<0.05). Carbohydrate, energy, fat intakes were significantly higher in cases, while folate, fiber, and vitamin E intakes were significantly lower in the case group, compared with the control group (p<0.05). BMI, cholesterol, and triglyceride values and dietary intakes of fiber and vitamin E were significantly associated with severity of psoriasis (p<0.05).
Conclusion: Serum lipid profile and dietary intake are substantially important in psoriasis severity. Therefore, close monitoring of lipid profile and BMI during admission and follow-up and dietary modification can improve the severity of psoriasis.
Type of Study: Original Article |
Subject:
Internal
Received: 2020/04/8 | Accepted: 2020/06/30 | Published: 2021/09/19
Received: 2020/04/8 | Accepted: 2020/06/30 | Published: 2021/09/19
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