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:: Volume 13 - Covid 19 Supplement 2 ::
Caspian J Intern Med 2022, 13 - Covid 19 Supplement 2: 161-172 Back to browse issues page
Covid-19 in kidney transplant recipients with immunosuppressive therapy: a case report and review article
Zahra Sheikhalipour , Masood Faghihdinevari , Hanieh Salehi-Pourmehr , Maryam Khameneh , Leila Vahedi
Liver and Gastrointestinal Diseases Research Center, Organ Transplant Registry, Tabriz University of Medical Sciences, Tabriz, Iran , vahedi.l49@gmail.com
Abstract:   (2992 Views)
Background: Since the outbreak of COVID-19, various treatments have been frequently reported for patients infected with this virus, especially in transplant patient recipients. Investigating o the literature and organ transplant patients with COVID-19, it could pave the way to understanding, handling, and treatment of COVID-19.
Methods: We had a brief review of the literature on immunosuppressive therapy in kidney transplants infected with COVID-19 based on the PubMed Database by keywords “kidney, transplant, COVID-19, and immunosuppress” after hospitalization of a kidney transplant reception infected with COVID-19. He had already been recorded in the Organ Transplant Registry (ID≠ 64510) of Tabriz University of Medical Sciences /Iran.
Results: We reported the clinical course of a 45-year-old man with a history of kidney transplant and immunotherapy who was infected with COVID-19 with respiratory infections and positive RT-PCR (Real-time polymerase chain reaction). He was treated with hydroxychloroquine, Kaletra, Cellcept, and Prednisolone for 5 days, and finally discharged from the hospital. In addition, the reviewing of 48 papers with 745 samples showed that immunosuppressant medications alone could be a therapeutic choice in kidney transplants infected with COVID-19 with careful management.
Conclusion: The patients with organ transplantation infected with COVID-19 may show different clinical signs, clinical course, and prognosis due to underlying diseases and the use of immunosuppressant medications. It might be best to continue taking the immunosuppressant medications but to modify them based on patients conditions such as clinical symptoms, laboratory results, paraclinical examinations.
Keywords: COVID- 19, Kidney transplant, Immunosuppressant, Review
Full-Text [PDF 314 kb]   (742 Downloads)    
Type of Study: Review Article | Subject: Infectious Diseases
Received: 2020/11/1 | Accepted: 2020/12/30 | Published: 2022/04/6
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Sheikhalipour Z, Faghihdinevari M, Salehi-Pourmehr H, Khameneh M, Vahedi L. Covid-19 in kidney transplant recipients with immunosuppressive therapy: a case report and review article. Caspian J Intern Med 2022; 13 :161-172
URL: http://caspjim.com/article-1-2573-en.html

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Volume 13 - Covid 19 Supplement 2 Back to browse issues page
Caspian Journal of Internal Medicine
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