Volume 12 - Case Supplement                   Caspian J Intern Med 2021, 12 - Case Supplement : 505-508 | Back to browse issues page


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Moudi E, Darzi M, Ramzani S, Akbarzadehpasha A. Xanthogranulomatous pyelonephritis combined with emphysematous pyelonephritis: A rare case report. Caspian J Intern Med 2021; 12 (S2) :505-508
URL: http://caspjim.com/article-1-2729-en.html
Cancer Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran , Aapasha812@yahoo.com
Abstract:   (2493 Views)
Background: Xanthogranulomatous pyelonephritis (XGP) is a rare and intense type of chronic kidney infection characterized by subversion of the renal tissue and its replacement by lipid- laden macrophages. XGP combined with emphysematous pyelonephritis (EPN) is rare and up until now only 7 cases with these  presentations have been reported; so abundant clinical skills and appropriate  radiographic imaging  is required to reach the correct diagnosis. In this report, we present a case with two uncommon variants of pyelonephritis.
Case Presentation: A 55-year-old female presented with a history of  type 2 diabetes mellitus, and a stroke leading to a left-sided hemiplegia state for 7 years, coronary artery bypass grafting (CABG), hypertension (HTN), seizure, progressive fatigue, loss of appetite , fecal and urinary incontinence and right costovertebral angle tenderness. According to clinical signs, symptoms and documentation of gas within the renal parenchyma on computed tomography (CT) of abdomen, of EPN diagnosis was suggested; however histopathologic evaluation showed acute emphysematous pyelonephritis on chronic xanthogranulomatous pyelonephritis.
Conclusion: EPN can emerge in a patient suffering from XPG which would add to the severity of the situation. In the case presented, concurrent underlying diseases such as diabetes mellitus, stroke, CABG, HTN along with severe fatigue and loss of appetite existed. Surgical treatment produces dramatic results.
Full-Text [PDF 155 kb]   (1025 Downloads)    
Type of Study: case report | Subject: Surgery
Received: 2021/01/25 | Accepted: 2021/04/26 | Published: 2021/07/24

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