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Caspian J Intern Med 2022, 13 - Covid 19 Supplement 2: 270-276 Back to browse issues page
Is Target Sign (Bull’s Eye Appearance) associated with adverse outcomes in COVID-19 patients? A Case Series and Literature Review
Mohammad-Mehdi Mehrabi Nejad , Mohammadreza Salehi , Javid Azadbakht , Zahra Jahani , Parastoo Veisi , Nahid Sadighi , Faeze Salahshour *
Department of Radiology, School of Medicine, Advanced Diagnostic and Interventional Radiology Research Center (ADIR), Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran , f-salahshour@sina.tums.ac.ir
Abstract:   (1418 Views)
Background: In COVID-19 pneumonia, chest CT scan plays a crucial role in diagnosing and closely monitoring lung parenchyma. The main reportedly chest CT features of novel coronavirus pneumonia (NCP) have been fully discussed in the literature, but there is still a paucity of reports on uncommon CT manifestations.  
Case presentation: Herewith, we have reported ten rRT-PCR confirmed COVID-19 patients with CT target signs (bull’s eye appearance); additionally, we have reviewed previously reported cases. Reviewing the literature, we found eight COVID-19 patients with target sign in the literature. 18 patients were included with a median age of 43. 11 (61%) patients were males. In 87% of patients, the lesions developed within the second-week post symptom onset. These patients mostly experienced an extended hospital stay (median = 10 days), with 53.8% of cases being admitted in ICU. The in-hospital mortality rate was 23%.
Conclusion: Our findings indicate that lesions with a bull’s eye appearance are not significantly associated with higher mortality in hospitalized COVID-19 patients.
Keywords: severe acute respiratory syndrome coronavirus 2, COVID-19, CT scan, pneumonia
Full-Text [PDF 347 kb]   (588 Downloads)    
Type of Study: Case Series | Subject: Infectious Diseases
Received: 2021/04/8 | Accepted: 2021/07/10 | Published: 2022/04/6
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Mehrabi Nejad M, Salehi M, Azadbakht J, Jahani Z, Veisi P, Sadighi N et al . Is Target Sign (Bull’s Eye Appearance) associated with adverse outcomes in COVID-19 patients? A Case Series and Literature Review. Caspian J Intern Med 2022; 13 :270-276
URL: http://caspjim.com/article-1-2841-en.html

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Volume 13 - Covid 19 Supplement 2 Back to browse issues page
Caspian Journal of Internal Medicine
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