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:: Volume 13, Issue 3 (Summer 2022) ::
Caspian J Intern Med 2022, 13(3): 582-588 Back to browse issues page
The association between Antihypertensive drugs and oral health- related quality of life in the elderly: results of Amirkola cohort study
Seyyedeh Fatemeh Langari , Seyed Reza Hosseini , Ali Bijani , Niloofar Jenabian , Mina Motalebnejad , Elham Mahmoodi , Zahra Sadat Madani , Fatemeh Sayadi , MohammadMehdi Naghibi Sistani , Reza Ghadimi , Fateme Baladi , Mohammad Hajimirzamohammad , Mahsa Mehryari , Atena Shirzad *
Department of oral and maxillofacial medicine, Oral Health Research Center, Health Research Institute. Babol University of Medical Sciences, Babol, Iran. , ats60dent@gmail.com
Abstract:   (1088 Views)
Background: Hypertension is one of the most common chronic diseases in the world. The prevalence of hypertension in the elderly is increasing. Patients with high blood pressure have to take medication throughout their lives. In this study, the relationship between antihypertensive drugs and oral health-related quality of life in the elderly was evaluated.
Methods: This modified cross-sectional study, which is the part of the second phase of the Amirkola Health and Ageing Project (AHAP), was performed on 900 elderly people. Participants included 300 people with hypertension under medical treatment, 300 people with hypertension without medication and 300 people with normal blood pressure. All patients’ blood pressure was recorded, and the standard xerostomia questionnaire and GOHAI questionnaire (Geriatric Oral Health Assessment Index) was completed for all participants. Then, the obtained data were analyzed by SPSS 17, whereby student’s t-test, ANOVA and chi square, Pearson correlation coefficient and logistic regression model were used. A p<0.05 was considered statistically significant.
Results: The mean GOHAI score in the three studied groups: hypertensive under medication treatment, hypertensive without medication treatment and normal blood pressure (51.1±7.4, 51.7±7.3, 51.1±7.5, respectively) did not differ significantly (P=0.533).The frequency of xerostomia was significantly different in the three groups (P=0.008). Among the antihypertensive drugs, the highest rate of xerostomia was due to the use of calcium channel blockers (31.1%) and diuretics (26.8%).
Conclusion: In our study, although antihypertensive medications were associated with xerostomia, they did not decrease the oral health-related quality of life.

Keywords: quality of life, xerostomia, elderly, anti hypertensive drugs
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Type of Study: Original Article | Subject: Dentistry
Received: 2021/08/29 | Accepted: 2022/02/21 | Published: 2022/06/1
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Langari S F, Hosseini S R, Bijani A, Jenabian N, Motalebnejad M, Mahmoodi E, et al . The association between Antihypertensive drugs and oral health- related quality of life in the elderly: results of Amirkola cohort study. Caspian J Intern Med 2022; 13 (3) :582-588
URL: http://caspjim.com/article-1-3079-en.html

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Volume 13, Issue 3 (Summer 2022) Back to browse issues page
Caspian Journal of Internal Medicine
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