Caspian Journal of Internal Medicine
Babol University of Medical Sciences
Fri, Nov 29, 2024
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Volume 14, Issue 2 (Spring 2023)
Caspian J Intern Med 2023, 14(2): 376-379 |
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Hosseini M, Asarzadegan F, Shafiee E, Alijanpour S. Trigeminal neuralgia: IncobotulinumtoxinA (Xeomin), can it decrease the pharmacological intervention? (A case series). Caspian J Intern Med 2023; 14 (2) :376-379
URL: http://caspjim.com/article-1-3161-en.html
URL: http://caspjim.com/article-1-3161-en.html
Department of Neurology, Shahid Beheshti University of Medical Sciences, Tehran, Iran , alijanpour.sh@live.com
Abstract: (1342 Views)
Background: Trigeminal neuralgia is one of the most disabling facial pain syndromes. In recent years' new therapeutic strategy, incobotulinumtoxin A has emerged. The aim of the current study was to determine the time and duration of pain in 3 cases with pharmacological treatment and incobotulinumtoxin A.
Case presentation: In three patients with different onsets, trigeminal neuralgia was diagnosed. Pain severity was assessed by the visual analogue scale. Patient demographics and clinical data were filled in a checklist. They were females with age ranging from 39 to 49 years. Two patients had normal MRI and one patient had no any recent MRI. One center and specialist injection Xeomin 50 units for one time. Despite long time oral treatment, their symptoms had no significant improvement, but after incobotulinumtoxin A injection, pain frequency, severity and duration decreased in patients.
Conclusion: Result showed that the frequency, severity and duration of pain attacks was efficiently decreased by incobotulinumtoxin A with low side-effects. Its complication and side-effect should be considered in the future.
Case presentation: In three patients with different onsets, trigeminal neuralgia was diagnosed. Pain severity was assessed by the visual analogue scale. Patient demographics and clinical data were filled in a checklist. They were females with age ranging from 39 to 49 years. Two patients had normal MRI and one patient had no any recent MRI. One center and specialist injection Xeomin 50 units for one time. Despite long time oral treatment, their symptoms had no significant improvement, but after incobotulinumtoxin A injection, pain frequency, severity and duration decreased in patients.
Conclusion: Result showed that the frequency, severity and duration of pain attacks was efficiently decreased by incobotulinumtoxin A with low side-effects. Its complication and side-effect should be considered in the future.
Type of Study: Case Series |
Subject:
Neurology
Received: 2021/10/15 | Accepted: 2021/12/25 | Published: 2023/03/8
Received: 2021/10/15 | Accepted: 2021/12/25 | Published: 2023/03/8
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