Caspian Journal of Internal Medicine
Babol University of Medical Sciences
Fri, Feb 21, 2025
[Archive]
Department of Oral and Maxillofacial surgery, The Dental College of Georgia at Augusta University, Augusta, Ga , SGHASEMI@augusta.edu
Abstract: (1757 Views)
Background: Focal epithelial hyperplasia (FEH) or Heck's disease is a condition of the oral mucosa defined by the asymptomatic presence of papules or nodules distributed in the oral mucosa, gingiva, tongue and lips. Heck's disease is most reported in the Native American and South African populations. It is mainly found in children with confirmed human papillomavirus (HPV) mostly HPV13 and 32. We report a rare case of Heck's disease in an Iranian-Turkmen girl with HPV6.
Case presentation: A 9-year-old Turkmen girl had esthetic and traumatic chief complaints caused by some enlarged lesions on her lips during the last six months. The patient did not have any systemic disease. Oral manifestations were white and pink nodules and papules on lips, buccal mucosa, and palate. Her mother had less than 10 similar lesions on her tongue and floor of the mouth that resolved, and only was papule was remained. HPV 6 was confirmed.
Conclusion: Patients with Heck's disease may be referred to an oral specialist, dermatologist, or otolaryngologist, so there should be enough knowledge about this condition among clinicians.
Case presentation: A 9-year-old Turkmen girl had esthetic and traumatic chief complaints caused by some enlarged lesions on her lips during the last six months. The patient did not have any systemic disease. Oral manifestations were white and pink nodules and papules on lips, buccal mucosa, and palate. Her mother had less than 10 similar lesions on her tongue and floor of the mouth that resolved, and only was papule was remained. HPV 6 was confirmed.
Conclusion: Patients with Heck's disease may be referred to an oral specialist, dermatologist, or otolaryngologist, so there should be enough knowledge about this condition among clinicians.
Keywords: Heck's disease, focal epithelial hyperplasia, Human papillomavirus, HPV6, Oral mucosa, Case report
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