Caspian Journal of Internal Medicine
Babol University of Medical Sciences
Thu, Mar 20, 2025
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Volume 15, Issue 2 (Spring 2024)
Caspian J Intern Med 2024, 15(2): 347-353 |
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Golsha R, Mazandarani M, Sohrabi A, Shirzad-Aski H, Kamalinia H, Rezaeifar A et al . Risk factors and treatment outcome of smear positive pulmonary tuberculosis patients: A five-year study in the North of Iran. Caspian J Intern Med 2024; 15 (2) :347-353
URL: http://caspjim.com/article-1-3695-en.html
URL: http://caspjim.com/article-1-3695-en.html
Roghieh Golsha 
, Mahdi Mazandarani , Ahmad Sohrabi , Hesamaddin Shirzad-Aski * , Hamidreza Kamalinia , Atefeh Rezaeifar , Mandana Fattahi
, Mahdi Mazandarani , Ahmad Sohrabi , Hesamaddin Shirzad-Aski * , Hamidreza Kamalinia , Atefeh Rezaeifar , Mandana Fattahi
Infectious Diseases Research Center, Golestan University of Medical Sciences, Gorgan, Iran , Shirzad_hessam@yahoo.com
Abstract: (1035 Views)
Background: It is essential to constantly review the risk factors and treatment outcomes of tuberculosis (TB). This study evaluated some important risk factors of TB over five years.
Methods: Between 2013 and 2018, all available information and possible risk factors related to TB patients were analyzed from the TB registry program of the health district of Gorgan, Iran.
Results: Among 349 TB patients, 194 (55.59%) were males and 167 (47.85%) had at least a comorbidity. The death rate was higher in the age group more than 65 years (p < 0.001), the low-educated group (P = 0.012), and patients with underlying diseases, especially diabetes (p < 0.001). In total, univariate and multivariate statistical analyzes showed that having comorbidity (OR = 4.34; 95% CI 1.49 – 13.49), as well as, being jobless (OR = 3.07; 95% CI 1.19 – 8.59) were the main factors influencing the adverse events.
Conclusion: According to the study, aging, underlying diseases, and cultural poverty include a higher share of the main risk factors for active TB and/or treatment outcomes. By considering these risk factors and training the medical staff continually, we can reduce the time of TB diagnosis, and prevent it from spreading.
Methods: Between 2013 and 2018, all available information and possible risk factors related to TB patients were analyzed from the TB registry program of the health district of Gorgan, Iran.
Results: Among 349 TB patients, 194 (55.59%) were males and 167 (47.85%) had at least a comorbidity. The death rate was higher in the age group more than 65 years (p < 0.001), the low-educated group (P = 0.012), and patients with underlying diseases, especially diabetes (p < 0.001). In total, univariate and multivariate statistical analyzes showed that having comorbidity (OR = 4.34; 95% CI 1.49 – 13.49), as well as, being jobless (OR = 3.07; 95% CI 1.19 – 8.59) were the main factors influencing the adverse events.
Conclusion: According to the study, aging, underlying diseases, and cultural poverty include a higher share of the main risk factors for active TB and/or treatment outcomes. By considering these risk factors and training the medical staff continually, we can reduce the time of TB diagnosis, and prevent it from spreading.
Type of Study: Short Communication |
Subject:
Infectious Diseases
Received: 2022/10/10 | Accepted: 2024/02/24 | Published: 2024/02/24
Received: 2022/10/10 | Accepted: 2024/02/24 | Published: 2024/02/24
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