Caspian Journal of Internal Medicine
Babol University of Medical Sciences
سه شنبه 27 خرداد 1404
[Archive]
دوره 16، شماره 3 - ( 3-1404 )
جلد 16 شماره 3 صفحات 443-437 |
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Aghapour S R, Mohammadi H, Aghapour S P, Farnoud K, Sharifzadeh Y. Comparing the results of knee osteoarthritis treatment with intra-articular injection of steroid (methylprednisolone) and hyaluronic acid. Caspian J Intern Med 2025; 16 (3) :437-443
URL: http://caspjim.com/article-1-4241-fa.html
URL: http://caspjim.com/article-1-4241-fa.html
Comparing the results of knee osteoarthritis treatment with intra-articular injection of steroid (methylprednisolone) and hyaluronic acid. . 1404; 16 (3) :437-443
چکیده: (20 مشاهده)
Background: Treatments for osteoarthritis, including steroids and nonsteroidal anti-inflammatory drugs, are not very satisfactory. Therefore, we decided to compare the therapeutic results of intra-articular injection of hyaluronic acid and methylprednisolone.
Methods: In this single-blind clinical trial, 132 patients with osteoarthritis of the knee were randomly assigned to two treatment groups; hyaluronic acid and methylprednisolone. Treatment results were measured based on the standard McMaster Universities Arthritis Index (WOMAC) questionnaire.
Results: Although the desired level of satisfaction was higher in the short-term in the methylprednisolone group and in the long-term in the hyaluronic acid group, however, these differences were not significant.
Conclusion: The recovery of patients is better with methylprednisolone injection in the short term and hyaluronic acid in the long term. However, since methylprednisolone has complications, it is recommended to consider hyaluronic acid as a suitable drug in the treatment process.
Methods: In this single-blind clinical trial, 132 patients with osteoarthritis of the knee were randomly assigned to two treatment groups; hyaluronic acid and methylprednisolone. Treatment results were measured based on the standard McMaster Universities Arthritis Index (WOMAC) questionnaire.
Results: Although the desired level of satisfaction was higher in the short-term in the methylprednisolone group and in the long-term in the hyaluronic acid group, however, these differences were not significant.
Conclusion: The recovery of patients is better with methylprednisolone injection in the short term and hyaluronic acid in the long term. However, since methylprednisolone has complications, it is recommended to consider hyaluronic acid as a suitable drug in the treatment process.
نوع مطالعه: Original Article |
دریافت: 1402/10/21 | پذیرش: 1403/4/17 | انتشار: 1404/3/30
دریافت: 1402/10/21 | پذیرش: 1403/4/17 | انتشار: 1404/3/30
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