Caspian Journal of Internal Medicine
Babol University of Medical Sciences
Sun, Oct 19, 2025
[Archive]
Volume 16, Issue 4 (Autumn 2025)
Caspian J Intern Med 2025, 16(4): 767-774 |
Back to browse issues page
Ethics code: IR.UMSHA.REC.1398.171
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Hosseini S K, Rind Baloch G M, Fathi Jouzdani A, Seif Rabiei M A, Hadei S K. CT angiography evaluation of epicardial fat volume and its association with coronary artery stenosis: A single-center cross-sectional study. Caspian J Intern Med 2025; 16 (4) :767-774
URL: http://caspjim.com/article-1-4512-en.html
URL: http://caspjim.com/article-1-4512-en.html
Seyed Kianoosh Hosseini 
, Ghulam Muhammad Rind Baloch , Ali Fathi Jouzdani * , Mohammad Ali Seif Rabiei , Seyed Kamaledin Hadei
, Ghulam Muhammad Rind Baloch , Ali Fathi Jouzdani * , Mohammad Ali Seif Rabiei , Seyed Kamaledin Hadei
USERN Office, Hamadan University of Medical Sciences, Hamadan, Iran. , ali.fathi77@gmail.com
Abstract: (22 Views)
Background: The relationship between epicardial fat and coronary stenosis has been a topic of recent discussion. This study aimed to determine the correlation between epicardial fat volume and coronary artery stenosis in patients undergoing CT angiography.
Methods: In this descriptive/cross-sectional study, 240 patients with low to moderate risk of CAD, referred to the CT angiography unit of Farshchian Hospital in Hamadan in 2023, were selected via the Census method. Coronary artery stenosis was assessed using a 128-slice multi-detector CT scan, while epicardial fat volume was measured using CT scan analysis. Statistical analyses were performed using SPSS software Version 21, with a significance level set at 0.05.
Results: The mean age of the patients was 54.69 years, with 52.5% being males. The mean epicardial fat volume was 76.64 ml, and 58.3% of the patients had coronary artery stenosis. The mean epicardial fat volume in patients with coronary stenosis was 82.82±31.41 ml, compared to 65.66±25.79 ml in those without stenosis (p<0.001). There was a significant positive correlation between epicardial fat volume and patients' age, calcium score, vessel score, and LDL levels. Additionally, the mean epicardial fat volume in patients with both obstructive and non-obstructive stenosis in the LAD and LCX was significantly higher than in vessels without stenosis (P < 0.05).
Conclusion: Epicardial fat volume is significantly associated with coronary artery stenosis and calcium score. Therefore, it can be utilized to determine and predict the presence and severity of coronary artery stenosis.
Methods: In this descriptive/cross-sectional study, 240 patients with low to moderate risk of CAD, referred to the CT angiography unit of Farshchian Hospital in Hamadan in 2023, were selected via the Census method. Coronary artery stenosis was assessed using a 128-slice multi-detector CT scan, while epicardial fat volume was measured using CT scan analysis. Statistical analyses were performed using SPSS software Version 21, with a significance level set at 0.05.
Results: The mean age of the patients was 54.69 years, with 52.5% being males. The mean epicardial fat volume was 76.64 ml, and 58.3% of the patients had coronary artery stenosis. The mean epicardial fat volume in patients with coronary stenosis was 82.82±31.41 ml, compared to 65.66±25.79 ml in those without stenosis (p<0.001). There was a significant positive correlation between epicardial fat volume and patients' age, calcium score, vessel score, and LDL levels. Additionally, the mean epicardial fat volume in patients with both obstructive and non-obstructive stenosis in the LAD and LCX was significantly higher than in vessels without stenosis (P < 0.05).
Conclusion: Epicardial fat volume is significantly associated with coronary artery stenosis and calcium score. Therefore, it can be utilized to determine and predict the presence and severity of coronary artery stenosis.
Policy Brief: Original Article |
Subject:
Cardiology
Received: 2024/09/11 | Accepted: 2025/01/18 | Published: 2025/09/18
Received: 2024/09/11 | Accepted: 2025/01/18 | Published: 2025/09/18
Send email to the article author
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
