Caspian Journal of Internal Medicine
Babol University of Medical Sciences
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Volume 12 - Case Supplement
Caspian J Intern Med 2021, 12 - Case Supplement : 482-486 |
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Alesaeidi S, Daraei M, Salami khanshan A, Zainaldain H. A multisystem syndrome compatible with systemic lupus erythematosus: Case report and review of literature. Caspian J Intern Med 2021; 12 (S2) :482-486
URL: http://caspjim.com/article-1-1844-en.html
URL: http://caspjim.com/article-1-1844-en.html
School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. , ahmad.23088@gmail.com
Abstract: (2235 Views)
Background: Abdominal pain is a routine symptom. Mesenteric arteritis, intestinal vasculitis, enteric vasculitis, mesenteric vasculitis, lupus peritonitis, and abdominal serositis are the possible differential diagnoses. Therefore, lupus enteritis has an uncertain outbreak.
Case Presentation: A 27-year-old woman presented with clinical presentation of peritonitis suggestive of acute abdominal crisis with three days history of fever, bloody diarrhea, nausea, vomiting and seizure. Further work up revealed microangiopathic hemolytic anemia, thrombocytopenia, proteinuria, polyserositis and her initial autoimmune panel all were negative. Since SLE was at the top of our diagnosis, we considered glucocorticoid and cyclophosphamide pulse therapy. After approximately two months of her initial presentation, when all of her symptoms subsided by initial therapy, her antinuclear antibody became positive at 1:320 titers and renal biopsy was compatible with lupus nephritis (stage III).
Conclusion: It is crucial to take the diagnosis of lupus into consideration, in case of any young female with multiorgan involvement even without positive antibody tests. As in this case, it took more than two months after initial presentation to confirm the diagnosis via renal biopsy and only after then, serum autoantibodies became seropositive
Case Presentation: A 27-year-old woman presented with clinical presentation of peritonitis suggestive of acute abdominal crisis with three days history of fever, bloody diarrhea, nausea, vomiting and seizure. Further work up revealed microangiopathic hemolytic anemia, thrombocytopenia, proteinuria, polyserositis and her initial autoimmune panel all were negative. Since SLE was at the top of our diagnosis, we considered glucocorticoid and cyclophosphamide pulse therapy. After approximately two months of her initial presentation, when all of her symptoms subsided by initial therapy, her antinuclear antibody became positive at 1:320 titers and renal biopsy was compatible with lupus nephritis (stage III).
Conclusion: It is crucial to take the diagnosis of lupus into consideration, in case of any young female with multiorgan involvement even without positive antibody tests. As in this case, it took more than two months after initial presentation to confirm the diagnosis via renal biopsy and only after then, serum autoantibodies became seropositive
Type of Study: case report |
Subject:
Reumatology
Received: 2019/04/10 | Accepted: 2020/08/15 | Published: 2021/07/24
Received: 2019/04/10 | Accepted: 2020/08/15 | Published: 2021/07/24
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