[Home ] [Archive]    
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 13, Issue 3 (Summer 2022) ::
Caspian J Intern Med 2022, 13(3): 447-457 Back to browse issues page
Global systematic review and meta-analysis of health-related quality of life in Behcet’s patients
Maryam Masoumi , Alireza Sharifi , Sepideh Rezaei , Sima Rafiei , Hossein Hosseinifard , Saghar Khani , Maryam Doustmehraban , Mona Rajabi , Zahra Beiramy Chomalou , Parisa Soori , Akbar Javan Biparva , Afsaneh Dehnad , Fatemeh Pashazadeh kan , Ahmad Ghashghaee *
Student Research Committee, Qazvin University of Medical Sciences, Qazvin, Iran , ahmad.ghashghaee1996@gmail.com
Abstract:   (826 Views)
Background: Behcet’s disease is a chronic fatal illness with a relapsing remitting nature and significant organ-threatening morbidity and mortality. The aim of this research was to examine studies which were conducted on investigation of prevalence of quality of life among patients with Behcet’s disease.
Methods: A total of 13 articles were extracted from four main databases including PubMed, EMBASE, Scopus, and Web of Science from the onset of 2000 to January 2021. All studies published in English with the purpose of examining quality of life (QOL) among patients with BD or investigating its main determinants were included.
Results: Totally, 1137 BD patients participated in 13 studies. Based on random effect analysis, the total score of physical health-related QOL was 46.7 (95% CI=41.26 to 52.13) and the total score of mental health-related QOL was 49.01 (95% CI=43.83 to 54.18) representing a moderate level of QOL among BD patients. Furthermore, weighted effect size analyses showed a significant correlation between QOL and variables such as patients’ age, gender, disease duration and depression (pvalue: 0.00).
Conclusion: As the symptoms of BD worsen over time, patients confront with more severe body pain, mobility restrictions, and difficulties in chewing, eating, speaking and swallowing which negatively affect social interactions of patients and reduce their QOL. Furthermore, depression was proved to act as a deteriorating factor for HRQOL among BD patients. Thus, patients need to be psychologically supported by a specialized team and be informed during the course of treatment to gain useful information about the disease, treatment approaches and coping strategies.
Keywords: Global, health-related quality of life, Behcet’s disease, systematic review.
Full-Text [PDF 498 kb]   (378 Downloads)    
Type of Study: Review Article | Subject: Reumatology
Received: 2021/06/12 | Accepted: 2021/12/8 | Published: 2022/06/1
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA



XML     Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Masoumi M, Sharifi A, Rezaei S, Rafiei S, Hosseinifard H, Khani S, et al . Global systematic review and meta-analysis of health-related quality of life in Behcet’s patients. Caspian J Intern Med. 2022; 13 (3) :447-457
URL: http://caspjim.com/article-1-2957-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 13, Issue 3 (Summer 2022) Back to browse issues page
Caspian Journal of Internal Medicine
Persian site map - English site map - Created in 0.04 seconds with 30 queries by YEKTAWEB 4463