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:: Volume 13 - Covid 19 Supplement 2 ::
Caspian J Intern Med 2022, 13 - Covid 19 Supplement 2: 211-220 Back to browse issues page
Clinical, demographic, and laboratory characteristics of COVID -19 infection and risk of in-hospital mortality. A single center study
Fatemeh Naseri Atashani , Elham Naseri , Esmaeil Zeinali , Roya Zamani , Aliakbar Salahshouri , Mohsen Ghourchibeigi , Parnaz Heidari , Ali Koushan , Narges Naseri Atashani , Behzad Heidari
Mobility Impairment Research Center, Babol University of Medical Sciences, Babol, Iran , bheidari6@gmail.com
Abstract:   (2125 Views)
Background: Despite advances in preventive measures, COVID -19 has spread and mortality continues due to delay in timely diagnosis. This problem is partly dependent on variations in disease characteristics, distribution of risk factors particularly comorbidities and demographic characteristics of patients. This study aimed to determine the clinical presentation and associated factors of mortality in patients hospitalized with COVID -19 infection.
Methods: Patients were divided into survivor and deceased groups, and clinical and laboratory findings and factors associated with mortality between the two groups were compared by calculating odds ratio (OR) with 95% confidence interval (95% CI).
Results: A total of 257 patients (female 45.1%) with a mean age of 59.8+15.7 years and a mean hospital stay of 4.89+3.57 days were studied. Diabetes, hypertension, cardiovascular disease and chronic renal disease (CRD) were found in 29.6%, 37.5%, 16.3% and 3.5% of all patients, respectively. Forty-one (16%) patients died. Factors such as age >50 years, coexisting CRD, serum creatinine > 2 mg/dl; SPO2 <70% lymphocytes < 20% during hospitalization were independently associated with mortality. The adjusted ORs (95% CI) were 10.08 (1.39-73); 4.51(1.15-17.61); 6 (1.14-31.5); 16.8(2.93-96.7); and 4.9(1.31-18.1), respectively. Most of the expected effective drugs were not associated with lower mortality.
Conclusion: These results indicate a high in-hospital mortality rate in COVID -19 patients. Some mortality factors occurring during hospitalization can be prevented by timely diagnosis and appropriate treatment.
Keywords: COVID-19, Mortality, Hospitalization, Elderly, Hypoxemia, Lymphopenia, Renal disease
Full-Text [PDF 296 kb]   (641 Downloads)    
Type of Study: Original Article | Subject: Microbiology
Received: 2021/10/12 | Accepted: 2021/11/30 | Published: 2022/04/6
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Naseri Atashani F, Naseri E, Zeinali E, Zamani R, Salahshouri A, Ghourchibeigi M, et al . Clinical, demographic, and laboratory characteristics of COVID -19 infection and risk of in-hospital mortality. A single center study. Caspian J Intern Med 2022; 13 :211-220
URL: http://caspjim.com/article-1-3155-en.html

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Volume 13 - Covid 19 Supplement 2 Back to browse issues page
Caspian Journal of Internal Medicine
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