Caspian Journal of Internal Medicine
Babol University of Medical Sciences
Fri, Jan 3, 2025
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Volume 15, Issue 4 (Autumn 2024)
Caspian J Intern Med 2024, 15(4): 729-734 |
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Emam M M, Abiyarghamsari M, Kazempour M, Haghighi-Morad M, Farsad F. Multiple sclerosis in a patient with Takayasu’s Arteritis:
A case report. Caspian J Intern Med 2024; 15 (4) :729-734
URL: http://caspjim.com/article-1-3876-en.html
URL: http://caspjim.com/article-1-3876-en.html
Mohammad Mehdi Emam 
, Mahdiye Abiyarghamsari , Muhanna Kazempour * , Maryam Haghighi-Morad , Farane Farsad
, Mahdiye Abiyarghamsari , Muhanna Kazempour * , Maryam Haghighi-Morad , Farane Farsad
Department of Rheumatology, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran , muhannakazempour@gmail.com
Abstract: (466 Views)
Background: Multiple sclerosis (MS) and Takayasu's arteritis (TAK) are two autoimmune diseases that affect the Central nervous system (CNS), but the relationship between them has not been established.
Case Presentation: Here we report the emergence of MS during treatment. Takayasu’s arteritis in a 24-year-old Iranian woman with a severe presentation. She was treated aggressively with IV methylprednisolone 1 g/day for 3 days and continued with oral prednisolone, also IV cyclophosphamide monthly. After 2 months, loss of vision led to a diagnosis of Optic neuritis (ON) caused by concomitant MS.
Conclusion: Differentiating CNS vasculitis associated with Takayasu's arthritis from coexisting MS affecting the CNS is challenging and what is important is to avoid giving a TNF inhibitor.
Case Presentation: Here we report the emergence of MS during treatment. Takayasu’s arteritis in a 24-year-old Iranian woman with a severe presentation. She was treated aggressively with IV methylprednisolone 1 g/day for 3 days and continued with oral prednisolone, also IV cyclophosphamide monthly. After 2 months, loss of vision led to a diagnosis of Optic neuritis (ON) caused by concomitant MS.
Conclusion: Differentiating CNS vasculitis associated with Takayasu's arthritis from coexisting MS affecting the CNS is challenging and what is important is to avoid giving a TNF inhibitor.
Type of Study: case report |
Subject:
Reumatology
Received: 2023/03/5 | Accepted: 2023/11/11 | Published: 2024/08/18
Received: 2023/03/5 | Accepted: 2023/11/11 | Published: 2024/08/18
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