Caspian Journal of Internal Medicine
Babol University of Medical Sciences
Fri, Mar 21, 2025
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Volume 16, Issue 1 (Winter 2025)
Caspian J Intern Med 2025, 16(1): 158-164 |
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Mirtabar S M, Barat S, Kheirkhah F, Mostafazadeh A, Shirafkan H, Pahlavan Z et al . Impact of anemia on the six-month trend of anxiety and depression in women with threatened abortion: A case-control retrospective cohort study. Caspian J Intern Med 2025; 16 (1) :158-164
URL: http://caspjim.com/article-1-4205-en.html
URL: http://caspjim.com/article-1-4205-en.html
Seyyedeh Mahboobeh Mirtabar 
, Shahnaz Barat , Farzan Kheirkhah , Amrolah Mostafazadeh , Hoda Shirafkan , Zeinab Pahlavan , Mahbobeh Faramarzi *
, Shahnaz Barat , Farzan Kheirkhah , Amrolah Mostafazadeh , Hoda Shirafkan , Zeinab Pahlavan , Mahbobeh Faramarzi *
Social Determinants of Health Research Center, Health Research Institute, Babol, Iran , mahbob330@yahoo.com
Abstract: (728 Views)
Background: Anemia in pregnancy is associated with psychiatric symptoms and poor psychiatric symptoms, this study investigates the 6-month trends of anxiety and birth outcomes. Considering the controversies surrounding the impact of anemia on psychiatric symptoms, this study investigates the 6-month trends of anxiety and depression in anemic pregnant women with threatened abortion (TA).
Methods: A case-control retrospective cohort study conducted among 282 participants who enrolled in a registry of pregnant women with TA in Babol city from December 2022 to October 2023. Fifty individuals with anemia (hemoglobin < 11 g/dL) who were matched with 50 without anemia based on age, pregnancies, education, and gestational age, were included. The BSI-18 (Brief Symptom Inventory) was used to assess depression, anxiety, and psychological distress at the beginning, three and six-month follow-ups.
Results: The prevalence of anemia among women diagnosed with TA was found to be 17.7%. At the beginning, compared to normal individuals, anemic women had higher rates of depression (32% vs. 14%), anxiety (34% vs. 22%), and psychological distress (66% vs. 48%). Moreover, at 3- and 6-month follow-ups, the frequency of psychiatric symptoms in anemic women was significantly higher. The Generalized Estimating Equations model showed that although both groups had a decreasing trend of frequency anemic women experience a slower rate of decrease in psychiatric symptoms compared to non-anemic women.
Conclusion: Anemia in women with TA is associated with high rates of depression, anxiety, and psychological distress, as well as a slow recovery rate.
Methods: A case-control retrospective cohort study conducted among 282 participants who enrolled in a registry of pregnant women with TA in Babol city from December 2022 to October 2023. Fifty individuals with anemia (hemoglobin < 11 g/dL) who were matched with 50 without anemia based on age, pregnancies, education, and gestational age, were included. The BSI-18 (Brief Symptom Inventory) was used to assess depression, anxiety, and psychological distress at the beginning, three and six-month follow-ups.
Results: The prevalence of anemia among women diagnosed with TA was found to be 17.7%. At the beginning, compared to normal individuals, anemic women had higher rates of depression (32% vs. 14%), anxiety (34% vs. 22%), and psychological distress (66% vs. 48%). Moreover, at 3- and 6-month follow-ups, the frequency of psychiatric symptoms in anemic women was significantly higher. The Generalized Estimating Equations model showed that although both groups had a decreasing trend of frequency anemic women experience a slower rate of decrease in psychiatric symptoms compared to non-anemic women.
Conclusion: Anemia in women with TA is associated with high rates of depression, anxiety, and psychological distress, as well as a slow recovery rate.
Type of Study: Original Article |
Subject:
Internal
Received: 2023/12/14 | Accepted: 2024/01/29 | Published: 2025/10/4
Received: 2023/12/14 | Accepted: 2024/01/29 | Published: 2025/10/4
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