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:: Volume 6, Issue 3 (7-2015) ::
Caspian J Intern Med 2015, 6(3): 161-164 Back to browse issues page
Low baseline serum albumin a predictor of anemia in patients on chronic hemodialysis
Behzad Heidari , Hasan Taheri , Karimollah Hajian-Tilaki , Mehdi Yolmeh , Roghayeh Akbari
Babol University of Medical SciencesBabol , Rghayeh.akbari@yahoo.com
Abstract:   (10909 Views)

 Background: Inflammatory process has a substantial contribution in the development of anemia in chronic hemodialysis patients. Low serum albumin in hemodialysis patients is considered a marker of inflammation. The present longitudinal study aimed to determine the relationship between low baseline serum albumin and future development of anemia.

 Methods: The population of this study consisted of all patients on standard maintenance hemodialysis for at least three months or longer. Patients were classified as high or low serum albumin level (≥ or < 3.9 gr/dl). All patients received the standard treatment of anemia. The main objective of this study was to compare the prevalence of anemia defined as hemoglobin levels < 11 gr/dl between the two study groups at the end of the study period.

 Results: A total of 82 patients (50% females) with mean±SD age of 55±16.8 years and mean dialysis duration of 5.2±4 years were followed-up for an average period of 10±1 (range, 8-11) months, however 48 patients with high serum albumin and 24 patients with low serum albumin group completed the study. At baseline, the two groups were similar regarding hemoglobin (9.8±1.2 vs 9.16±1.6 gr/dl, P=0.95) levels. At endpoint, prevalence of anemia in high albumin group was significantly lower than the low albumin group (50% versus 83.3% P=0.005).

 Conclusion: The findings of this study indicate that low serum albumin in hemodialysis patients is a predictor of anemia indicating unresponsiveness to conventional treatment of anemia.


Keywords: Hemodialysis, Anemia, Serum Albumin
Full-Text [PDF 231 kb]   (3047 Downloads)    
Type of Study: Original Article | Subject: Nephrology
Received: 2015/06/10 | Accepted: 2015/06/22 | Published: 2015/06/22
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Heidari B, Taheri H, Hajian-Tilaki K, Yolmeh M, Akbari R. Low baseline serum albumin a predictor of anemia in patients on chronic hemodialysis. Caspian J Intern Med 2015; 6 (3) :161-164
URL: http://caspjim.com/article-1-559-en.html

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Volume 6, Issue 3 (7-2015) Back to browse issues page
Caspian Journal of Internal Medicine
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